{"created":"2023-07-27T06:50:20.844130+00:00","id":43091,"links":{},"metadata":{"_buckets":{"deposit":"a6cb7147-8ec4-4ef4-93c4-ed934638d898"},"_deposit":{"created_by":18,"id":"43091","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"43091"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00043091","sets":["2812:2813:2822"]},"author_link":["69","86411"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-05-08","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2009-2011","bibliographic_titles":[{"bibliographic_title":"平成23(2011)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2011 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ラット坐骨神経切断時に細胞外に放出されることが推測される分子を探索し、その候補として糖タンパクnmb(Glycoprotein non-metastatic melanoma B : Gpnmb)を同定した。Gpnmbは坐骨神経切断端に浸潤するマクロファージに検出された。さらに、正常ラットの脊髄後角I、II層のミクログリア細胞にも存在した。これらの結果から、Gpnmbは痛み情報伝達の調節に関与することが示唆された。","subitem_description_type":"Abstract"},{"subitem_description":"We explored genes whose protein products were assumed to be released into the extracellular space after axotomy of rat sciatic nerve, and identified glycoprotein non-metastatic melanoma B(Gpnmb) as a candidate. Gpnmb expression was detected in infiltrating macrophages in the nerve ends. Also, Gpnmb was expressed in microglia in the layers I and II of the spinal dorsal horn of normal rats. These results suggest that Gpnmb might be involved in the modulation of pain transduction.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:21600002, 研究期間(年度):2009-2011","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「損傷神経に誘導される新規蛋白がイオンチャネル活動調節・痛み情報伝達に果たす役割」課題番号21600002\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-21600002/21600002seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00049438","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=00210633"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=00210633","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21600002/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21600002/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-21600002/21600002seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-21600002/21600002seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-12-22"}],"displaytype":"detail","filename":"CH-PR-YOKOYAMA-S-kaken 2012-6p.pdf","filesize":[{"value":"406.0 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"CH-PR-YOKOYAMA-S-kaken 2012-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/43091/files/CH-PR-YOKOYAMA-S-kaken 2012-6p.pdf"},"version_id":"28cac0ab-35d8-498e-ae77-ddb1d1fa1a26"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"損傷神経に誘導される新規蛋白がイオンチャネル活動調節・痛み情報伝達に果たす役割","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"損傷神経に誘導される新規蛋白がイオンチャネル活動調節・痛み情報伝達に果たす役割"},{"subitem_title":"Identification of novel nerve injury-induced proteins and their roles in ion channel modulation and pain transduction","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2822"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-12-22"},"publish_date":"2017-12-22","publish_status":"0","recid":"43091","relation_version_is_last":true,"title":["損傷神経に誘導される新規蛋白がイオンチャネル活動調節・痛み情報伝達に果たす役割"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:29:07.507535+00:00"}