@article{oai:kanazawa-u.repo.nii.ac.jp:00043250,
 author = {東, 朋美 and 大倉, 徳幸 and 藤村, 政樹 and 西條, 淸史 and 早川, 和一 and 小林, 史彦 and 道上, 義正 and 人見, 嘉哲 and 中村, 裕之 and Higashi, Tomomi and Ohkura, Noriyuki and Fujimura, Masaki and Nakai, Satoshi and Honda, Yasushi and Saijoh, Kiyofumi and Hayakawa, Kazuichi and Kobayashi, Fumihisa and Michigami, Yoshimasa and Olando, Anyenda Enoch and Hitomi, Yoshiaki and Nakamura, Hiroyuki},
 journal = {Atmospheric Environment},
 month = {Nov},
 note = {Asian dust, known as kosa in Japanese, is a major public health concern. In this panel study, we evaluated the effects of exposure to kosa on daily cough occurrence. The study subjects were 86 patients being treated for asthma, cough variant asthma, or atopic cough in Kanazawa University Hospital from January 2011 to June 2011. Daily mean concentrations of kosa and spherical particles were obtained from light detection and ranging (LIDAR) measurements, and were categorized from Grade 1 (0 μg/m3) to 5 (over 100 μg/m3). The association between kosa and cough was analyzed by logistic regression with a generalized estimating equation. Kosa effects on cough were seen for all Grades with potential time lag effect. Particularly at Lag 0 (the day of exposure), a dose-response relationship was observed: the odds ratios for Grades 2, 3, 4, and 5 above the referent (Grade 1) were 1.111 (95% confidence interval (CI): 0.995-1.239), 1.171 (95% CI: 1.006-1.363), 1.357 (95% CI: 1.029-1.788), and 1.414 (95% CI: 0.983-2.036), respectively. Among the patients without asthma, the association was higher: the odds ratios for Grades 2, 3, 4 and 5 were 1.223 (95% CI: 0.999-1.497), 1.309 (95% CI: 0.987-1.737), 1.738 (95% CI: 1.029-2.935) and 2.403 (95% CI: 1.158-4.985), respectively. These associations remained after adjusting for the concentration of spherical particles or particulate matter with an aerodynamic diameter of less than 2.5 μm (PM2.5). Our findings demonstrate that kosa is an environmental factor which induces cough in a dose-response relationship. © 2014 Elsevier B.V., Embargo Period 12 months, 金沢大学医薬保健研究域医学系},
 pages = {544--551},
 title = {Reprint of: Effects of Asian dust on daily cough occurrence in patients with chronic cough: A panel study},
 volume = {97},
 year = {2014}
}