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Incorporation of NAD into fixed cell nuclei
https://doi.org/10.24517/00049835
https://doi.org/10.24517/00049835ced0b383-cc6d-4588-bba7-6777c70820d9
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-ISEKI-S-263.pdf (2.5 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2018-01-25 | |||||||
| タイトル | ||||||||
| タイトル | Incorporation of NAD into fixed cell nuclei | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| ID登録 | ||||||||
| ID登録 | 10.24517/00049835 | |||||||
| ID登録タイプ | JaLC | |||||||
| 著者 |
Iseki, Shoichi
× Iseki, Shoichi |
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| 著者別表示 |
井関, 尚一
× 井関, 尚一
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| 提供者所属 | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | 金沢大学医薬保健研究域医学系 | |||||||
| 書誌情報 |
Cell Biology International Reports 巻 11, 号 4, p. 263-272, 発行日 1987 |
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| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0309-1651 | |||||||
| NCID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA00600025 | |||||||
| DOI | ||||||||
| 関連タイプ | isIdenticalTo | |||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | 10.1016/0309-1651(87)90087-7 | |||||||
| 出版者 | ||||||||
| 出版者 | Wiley Open Access | |||||||
| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Incorporation of NAD into the nuclei was determined autoradiographically in cultured HeLa cells and in cryostat sections of rat organs by incubating them with 3H-NAD after fixation with various agents. Acetone fixation was the best to render the cells permeable to NAD while preserving the cell's enzymatic activity to incorporate NAD into nuclear macromolecules. Various evidence supported that such incorporation of NAD is due mostly to the synthesis of poly (ADP-ribose) on chromatin proteins. In the sections of rat jejunum and esophagus the rate of NAD incorporation was higher in the actively proliferating cell nuclei than in the differentiated cell nuclei within the same epithelia. These results suggested that the capacity of the cells to synthesize poly (ADP-ribose) is associated with cell growth and differentiation. © 1987. | |||||||
| 権利 | ||||||||
| 権利情報 | Copyright © 1987 Wiley | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
