{"created":"2023-07-27T06:50:35.449327+00:00","id":43555,"links":{},"metadata":{"_buckets":{"deposit":"78b7a005-2048-4a60-a942-4627c26bc88d"},"_deposit":{"created_by":18,"id":"43555","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"43555"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00043555","sets":["2812:2813:2816"]},"author_link":["71331","71332"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-06-06","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2015-04-01 – 2018-03-31","bibliographic_titles":[{"bibliographic_title":"平成29(2017)年度 科学研究費補助金 挑戦的萌芽研究 研究成果報告書"},{"bibliographic_title":"2017 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"肝炎、肝がん発生の原因ウイルスであるヒトＢ型肝炎ウイルス（HBV）のLife cycleを理解することは、このウイルスの感染・増殖を阻止する新たな方策を探る上で大切である。本研究では、まだあまりよくわかっていないHBVの肝細胞特異的な感染の分子機構を解明する足がかりとして、また、感染防御・制御のための抗HBV創薬の基盤として、新たに作製したiPS細胞のなかからから分化誘導後の肝細胞でより効率がよく再現性の高い安定したHBV in vitro感染系を確立した。","subitem_description_type":"Abstract"},{"subitem_description":"Understanding the Life cycle of human hepatitis B virus (HBV), the causal virus of hepatitis and liver cancer, is important in exploring new ways to prevent the infection and proliferation of HBV. In this study, as a foothold to elucidate the molecular mechanism of hepatocyte-specific infection of HBV which is not well understood yet, and as a basis for anti-HBV drug discovery, we established HBV in vitro infection system with more efficient and reproducible effect on differentiated hepatocytes from newly prepared iPS cells.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:15K15140, 研究期間(年度):2015-04-01 – 2018-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「B型肝炎ウイルスのin vitro 感染系の確立と感染防御」課題番号15K15140\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-15K15140/15K15140seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学がん進展制御研究所","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00049897","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=20178122"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=20178122","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K15140/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K15140/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-15K15140/15K15140seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-15K15140/15K15140seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-04-05"}],"displaytype":"detail","filename":"CA-PR-KUROKI-K-kaken 2018-4p.pdf","filesize":[{"value":"537.8 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"CA-PR-KUROKI-K-kaken 2018-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/43555/files/CA-PR-KUROKI-K-kaken 2018-4p.pdf"},"version_id":"4aba2c35-cf85-406b-b3e5-1fea14f5b8d2"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"B型肝炎ウイルスのin vitro 感染系の確立と感染防御","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"B型肝炎ウイルスのin vitro 感染系の確立と感染防御"},{"subitem_title":"Establishment of in vitro infection system of hepatitis B virus and infection prevention","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2816"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-04-06"},"publish_date":"2019-04-06","publish_status":"0","recid":"43555","relation_version_is_last":true,"title":["B型肝炎ウイルスのin vitro 感染系の確立と感染防御"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:03:31.277484+00:00"}