{"created":"2023-07-27T06:50:35.493880+00:00","id":43556,"links":{},"metadata":{"_buckets":{"deposit":"0be28d6d-d20e-4b68-938e-69afbbed2aff"},"_deposit":{"created_by":18,"id":"43556","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"43556"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00043556","sets":["2812:2813:2821"]},"author_link":["71331","71332"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-06-04","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2010-2012","bibliographic_titles":[{"bibliographic_title":"平成24(2012)年度 科学研究費補助金 挑戦的萌芽研究 研究成果報告書"},{"bibliographic_title":"2012 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"B型肝炎ウイルス感染機構研究のための新規B型肝炎ウイルスベクターの作製およびダックB型肝炎ウイルス(DHBV)の感染に関わる宿主因子の同定とB型肝炎ウイルスのin vitro感染系の確立を試みた。その結果、分泌型ルシフェラーゼ遺伝子を組込んだB型肝炎ウイルスの効率的な産生に成功した。また、DHBVの感染に関わる宿主因子は同定できていないが、ヒト肝がん由来細胞株HuH7がin vitro感染系樹立に有望であることがわかった。","subitem_description_type":"Abstract"},{"subitem_description":"For the study of entry pathway of hepatitis B viruses, we have constructed novel hepatitis B virus vectors and attempted to identify the host molecules related to the entry pathway and to establish in vitro infection systems for these viruses. As the results, we could construct novel hepatitis B virus vectors containing secretion-type luciferases as reporter genes. Unfortunately, we could not identify the host molecules relate to DHBV infection, but we were able to find human hepatoma cell HuH7 as HBV susceptible cells under the culture condition containing 2% DMSO.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:22659090, 研究期間(年度):2010-2012","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「B型肝炎ウイルス感染の分子機構」課題番号22659090\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22659090/22659090seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学がん進展制御研究所","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00049898","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学がん進展制御研究所"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=20178122"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=20178122","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22659090/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22659090/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22659090/22659090seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22659090/22659090seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-01-29"}],"displaytype":"detail","filename":"CA-PR-KUROKI-K-kaken 2013-4p.pdf","filesize":[{"value":"542.6 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"CA-PR-KUROKI-K-kaken 2013-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/43556/files/CA-PR-KUROKI-K-kaken 2013-4p.pdf"},"version_id":"861cd836-6b9d-4ed5-9428-476a41682b0c"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"B型肝炎ウイルス感染の分子機構","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"B型肝炎ウイルス感染の分子機構"},{"subitem_title":"Molecular mechanism of the infection of hepatitis B viruses","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2821"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-01-29"},"publish_date":"2018-01-29","publish_status":"0","recid":"43556","relation_version_is_last":true,"title":["B型肝炎ウイルス感染の分子機構"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:42:44.270660+00:00"}