{"created":"2023-07-27T06:50:43.282560+00:00","id":43745,"links":{},"metadata":{"_buckets":{"deposit":"447a0e5b-4685-4499-9a75-e9ff2f038689"},"_deposit":{"created_by":18,"id":"43745","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"43745"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00043745","sets":["2812:2813:2825"]},"author_link":["71948","71947"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-04-10","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2007-2008","bibliographic_titles":[{"bibliographic_title":"平成20(2008)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2008 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"消化器がんの発生過程では胃や大腸の粘膜上皮細胞が腫瘍化することとともに、腫瘍細胞周囲にマクロファージが浸潤して活性化することが重要であると考えられていた。本研究では、腸管腫瘍発生マウスモデルでマクロファージを欠損させると腫瘍発生が抑制されることを明らかにした。さらに、マクロファージ浸潤に関与すると考えられたケモカインCXCL14の遺伝子ノックアウトマウスを作製して解析した結果、CXCL14は腫瘍組織へのマクロファージ浸潤に関与していない可能性が示された。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19790285, 研究期間(年度):2007-2008","subitem_description_type":"Other"},{"subitem_description":"出典：「消化器腫瘍発生におけるCXCL14および組織マクロファージの役割」研究成果報告書　課題番号19790285\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19790285/19790285seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00050087","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学がん進展制御研究所"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=80362515"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=80362515","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19790285/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19790285/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19790285/19790285seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19790285/19790285seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-09"}],"displaytype":"detail","filename":"CA-PR-OSHIMA-H-kaken 2009-4p.pdf","filesize":[{"value":"2.5 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"CA-PR-OSHIMA-H-kaken 2009-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/43745/files/CA-PR-OSHIMA-H-kaken 2009-4p.pdf"},"version_id":"4c619e15-0292-4690-9695-65e4416d8a43"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"消化器腫瘍発生におけるCXCL14および組織マクロファージの役割","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"消化器腫瘍発生におけるCXCL14および組織マクロファージの役割"},{"subitem_title":"CXCL14 and tissue macrophages in gastrointestinal tumorigenesis","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2825"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-02-09"},"publish_date":"2018-02-09","publish_status":"0","recid":"43745","relation_version_is_last":true,"title":["消化器腫瘍発生におけるCXCL14および組織マクロファージの役割"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T14:15:22.987897+00:00"}