{"created":"2023-07-27T06:50:45.517774+00:00","id":43797,"links":{},"metadata":{"_buckets":{"deposit":"06a388c4-6675-42f8-a22d-3c50bacea2fc"},"_deposit":{"created_by":18,"id":"43797","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"43797"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00043797","sets":["2812:2813:2821"]},"author_link":["72138","72136"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-04-22","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2011-2012","bibliographic_titles":[{"bibliographic_title":"平成24(2012)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2012 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ウイルス感染モデルマウスを用いたスクリーニングによって、JmjCファミリーに属する遺伝子の約半数が癌の原因遺伝子候補として発見された。そのうちの1つJmjd5に関して、遺伝子改変マウス(Jmjd5^囗^)の表現型解析を行った結果、Jmjd5はp21遺伝子発現のエピジェネティックな制御因子の1つとして胚細胞の増殖に必須な遺伝子である事を2012年、Development誌で報告した。","subitem_description_type":"Abstract"},{"subitem_description":"Our retroviral insertional mutagenesis in mice showed frequent identification of JmjC family genes as novel candidates cancer-related genes. Jmjd5, one of the family genes, was also a target for the retrovirus, and we generated Jmjd5-deficientmice (Jmjd5△囗△) to investigate the physiological role of Jmjd5. We showed that Jmjd5 was involved in embryonic cell proliferation by fine-tuning the expression of p21 (Ishimura et al., Development 2012).","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:23790220, 研究期間(年度):2011-2012","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「ウイルス挿入変異法で同定された新規がん関連遺伝子Jmjd5の機能解析」課題番号23790220\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-23790220/23790220seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学がん進展制御研究所","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00050139","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学がん進展制御研究所"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=80375261"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=80375261","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23790220/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23790220/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-23790220/23790220seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-23790220/23790220seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-16"}],"displaytype":"detail","filename":"CA-PR-ISHIMURA-A-kaken 2013-4p.pdf","filesize":[{"value":"603.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"CA-PR-ISHIMURA-A-kaken 2013-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/43797/files/CA-PR-ISHIMURA-A-kaken 2013-4p.pdf"},"version_id":"5a742eb9-6c67-498f-9831-f8211e8baacb"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ウイルス挿入変異法で同定された新規がん関連遺伝子Jmjd5の機能解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ウイルス挿入変異法で同定された新規がん関連遺伝子Jmjd5の機能解析"},{"subitem_title":"Functional analysis of Jmjd5, a candidate cancer-related gene identified by retroviral insertional mutagenesis","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2821"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-02-16"},"publish_date":"2018-02-16","publish_status":"0","recid":"43797","relation_version_is_last":true,"title":["ウイルス挿入変異法で同定された新規がん関連遺伝子Jmjd5の機能解析"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:42:40.296472+00:00"}