{"created":"2023-07-27T06:50:53.005550+00:00","id":44044,"links":{},"metadata":{"_buckets":{"deposit":"4d5c2e2b-e355-4cf7-a125-9f64be1a2f3e"},"_deposit":{"created_by":18,"id":"44044","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"44044"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00044044","sets":["2812:2813:2821"]},"author_link":["73701","19995"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-04-18","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2010-2012","bibliographic_titles":[{"bibliographic_title":"平成24(2012)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2012 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"肝細胞癌の分子標的治療開始後の腫瘍血管の拡張所見が治療有効例の予測に応用可能と考えられた。Perfusion CTによる治療後早期の血流パラメータ値の変化と長期経過後の腫瘍の画像上変化との間には有意な相関は得られなかった。一方、Dual-Energy CTによる腫瘍内ヨード量定量値は腫瘍の血流と関連があることが示され、早期治療効果判定のバイオマーカーとして使用できる可能性が示唆された。","subitem_description_type":"Abstract"},{"subitem_description":"Dilatation of intratumoral vessels on multiphasic contrast enhanced CT was estimated to be one of the key findings for prediction of early therapeutic effect evaluation of molecular-targeting therapy for hepatocellular carcinoma (HCC). There are no significant correlation between hemodynamic parameters of CT perfusion just after starting of molecular-targeting therapy for HCC and long term therapeutic effect of it. In contrast, intratumoral iodine measurement obtained by dual-energy CT technique might be used as surrogate marker for early prediction of therapeutic effect of molecular targeting therapy for HCC.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:22591319, 研究期間(年度):2010-2012","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「固形癌分子標的治療の早期客観的治療効果判定法の確立」課題番号22591319\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22591319/22591319seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域保健学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00050386","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学医薬保健研究域保健学系"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=30313638"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=30313638","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22591319/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22591319/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22591319/22591319seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22591319/22591319seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-19"}],"displaytype":"detail","filename":"ME-PR-KOBAYASHI-S-kaken 2013-5p.pdf","filesize":[{"value":"381.5 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-KOBAYASHI-S-kaken 2013-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/44044/files/ME-PR-KOBAYASHI-S-kaken 2013-5p.pdf"},"version_id":"6059ae1b-7073-4611-818d-05886085f438"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"固形癌分子標的治療の早期客観的治療効果判定法の確立","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"固形癌分子標的治療の早期客観的治療効果判定法の確立"},{"subitem_title":"Early prediction of therapeutic effect of molecular targeting therapy for solid malignant tumor with imaging biomarkers","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2821"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-03-19"},"publish_date":"2018-03-19","publish_status":"0","recid":"44044","relation_version_is_last":true,"title":["固形癌分子標的治療の早期客観的治療効果判定法の確立"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:41:45.639137+00:00"}