{"created":"2023-07-27T06:51:00.835823+00:00","id":44251,"links":{},"metadata":{"_buckets":{"deposit":"bef4d653-03c9-4dfb-a983-74bd6d31994e"},"_deposit":{"created_by":18,"id":"44251","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"44251"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00044251","sets":["2812:2813:2825"]},"author_link":["48163","74413"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-05-21","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2007-2008","bibliographic_titles":[{"bibliographic_title":"平成20(2008)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2008 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本研究課題では、様々な組織幹細胞システムの制御機構における共通分子基盤の解明を目的とし、Spred-1に着目して造血幹細胞と色素幹細胞システムを中心に解析を行なった。Spred-1欠損マウスの解析から、血液系ではSpred-1はサイトカインである幹細胞因子(SCF)による刺激を抑制的に制御することによって造血幹細胞とその維持・分化の場所であるニッチとの親和性を調節していることが示唆された。一方色素系でも同様にSpred-1欠損マウスを用いた解析を行なった結果、色素細胞が過剰に増殖していることを明らかにした。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19790775, 研究期間(年度):2007-2008","subitem_description_type":"Other"},{"subitem_description":"出典：「色素幹細胞におけるSpred-1の機能と組織幹細胞制御機構の共通分子基盤の解明」研究成果報告書　課題番号19790775\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19790775/19790775seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00050593","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学がん進展制御研究所"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=00447343"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=00447343","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19790775/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19790775/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19790775/19790775seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19790775/19790775seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-04-19"}],"displaytype":"detail","filename":"CA-PR-TADOKORO-Y-kaken 2009-5p.pdf","filesize":[{"value":"249.8 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"CA-PR-TADOKORO-Y-kaken 2009-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/44251/files/CA-PR-TADOKORO-Y-kaken 2009-5p.pdf"},"version_id":"a1e02e36-4b0a-49c7-a9bb-5af51f4f8a14"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"色素幹細胞におけるSpred-1の機能と組織幹細胞制御機構の共通分子基盤の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"色素幹細胞におけるSpred-1の機能と組織幹細胞制御機構の共通分子基盤の解明"},{"subitem_title":"Analysis of functions of Spred-1 in melanocyte stem cells and common molecular mechanisms in tissue-specific stem cell regulations","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2825"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-04-19"},"publish_date":"2018-04-19","publish_status":"0","recid":"44251","relation_version_is_last":true,"title":["色素幹細胞におけるSpred-1の機能と組織幹細胞制御機構の共通分子基盤の解明"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T14:15:11.962369+00:00"}