{"created":"2023-07-27T06:51:02.732284+00:00","id":44294,"links":{},"metadata":{"_buckets":{"deposit":"f9fa9ae3-17cb-4418-b59f-41e292e265f4"},"_deposit":{"created_by":18,"id":"44294","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"44294"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00044294","sets":["2812:2813:2821"]},"author_link":["74756","273"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-04-03","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2010-2012","bibliographic_titles":[{"bibliographic_title":"平成24(2012)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2012 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"157名のサルコメア遺伝子変異保因者を検出し、そのうち107名について心エコー図検査指標を経時的解析した。7年間の観察期間中、12名に左室収縮不全が認められた。対象をミオシン結合蛋白C遺伝子保因者(MYBPC3群)と非ミオシン結合蛋白C遺伝子保因者(non-MYBPC3群)とに分けてカプランマイヤー法で解析した所、non-MYBPC3群はMYBPC3群と比較して、より高頻度に左室収縮不全をきたすことが判明した。","subitem_description_type":"Abstract"},{"subitem_description":"The study included 157 sarcomere gene mutation carriers, and 107 subjects underwent serial echocardiograms. At a mean follow-up of 7 years, 12 subjects experienced systolic dysfunction. When the subjects were divided into MYBPC3 and non-MYBPC3 mutation carriers, the rate of systolic dysfunction was higher in the non-MYBPC3 group than in MYBPC3 group.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:22590808, 研究期間(年度):2010-2012","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「肥大型及び拡張型心筋症の網羅的遺伝子解析によるテーラーメード治療の確立」課題番号22590808\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22590808/22590808seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00050636","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学医薬保健研究域保健学系"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=40361993"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=40361993","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22590808/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22590808/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22590808/22590808seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22590808/22590808seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-04-26"}],"displaytype":"detail","filename":"ME-PR-FUJINO-N-kaken 2013-5p.pdf","filesize":[{"value":"471.2 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-FUJINO-N-kaken 2013-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/44294/files/ME-PR-FUJINO-N-kaken 2013-5p.pdf"},"version_id":"271cfb7b-4e40-4ed1-ba01-96d012180cce"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"肥大型及び拡張型心筋症の網羅的遺伝子解析によるテーラーメード治療の確立","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"肥大型及び拡張型心筋症の網羅的遺伝子解析によるテーラーメード治療の確立"},{"subitem_title":"Research of the tailor-maid treatment of hypertrophic and dilated cardiomyopathy by comprehensive genetic analysis","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2821"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-04-26"},"publish_date":"2018-04-26","publish_status":"0","recid":"44294","relation_version_is_last":true,"title":["肥大型及び拡張型心筋症の網羅的遺伝子解析によるテーラーメード治療の確立"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:41:41.426139+00:00"}