{"created":"2023-07-27T06:51:05.527929+00:00","id":44358,"links":{},"metadata":{"_buckets":{"deposit":"53802478-8e7f-4322-9ad8-8a6b4692b5fb"},"_deposit":{"created_by":18,"id":"44358","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"44358"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00044358","sets":["2812:2813:2816"]},"author_link":["75505","292"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-05-30","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2015-04-01 - 2018-03-31","bibliographic_titles":[{"bibliographic_title":"平成29(2017)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2017 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"肺移植における，微弱磁場環境下と不凍物質添加による過冷却および冷凍保存法の有用性を研究した。ラットを用い，24時間保存後同種移植を行い，移植肺でのエネルギー代謝や再灌流障害の程度を比較した。【過冷却】微弱磁場下，-2℃保存の移植肺は、4℃単純冷却保存と比べエネルギー代謝や再灌流障害が抑制され，肺摘出直後移植の移植肺と比べほぼ同等であった。微弱磁場環境下で，保存液にAFPを添加しても有意な上乗せ効果はなかった。4℃単純冷却肺保存では不凍タンパク，特にAFGPは肺保存状態を改善する可能性があることが示された。【冷凍】-10℃での冷凍肺保存におけるCAS，不凍タンパク添加の有意な効果はなかった。","subitem_description_type":"Abstract"},{"subitem_description":"The effectiveness of subzero lung preservation in a variable magnetic field using CAS with anti-freeze protein was examined.\nWe prepared a lung allograft model in rats. After reperfusion for 2 hours following 24-hour preservation, we evaluated the energy charge and reperfusion injury values of the transplanted lung in four groups. Group A: without preservation, Group B: at 4°C in a normal refrigerator, Group C: at -2°C in a CAS, Group D: 60 mg/ml of AFP to the preservation solution used for Group C. The outcome of Group C was better than that of Group B and equivalent to that of Group A and Group D. CAS was effective and adding AFP resulted in only a small added effectiveness. In addition, the effectiveness of anti-freeze proteins (AFP and AFGP) was examined in the same model as Group B. Anti-freeze proteins, in particular AFGP, are relatively effective. Furthermore, a separate experiment demonstrated that CAS with AFP was not significantly effective for -10°C lung cryopreservation.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:15K10021, 研究期間(年度):2015-04-01 - 2018-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「微弱磁場環境下・不凍物質添加低温保存肺の移植に関する研究」課題番号15K10021\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-15K10021/15K10021seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00050700","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=80361989"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=80361989","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K10021/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K10021/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-15K10021/15K10021seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-15K10021/15K10021seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-04-11"}],"displaytype":"detail","filename":"ME-PR-MATSUMOTO-I-kaken 2018-4p.pdf","filesize":[{"value":"172.1 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-MATSUMOTO-I-kaken 2018-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/44358/files/ME-PR-MATSUMOTO-I-kaken 2018-4p.pdf"},"version_id":"3cbdb15b-e687-48ce-96b5-21b54a0a2161"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"微弱磁場環境下・不凍物質添加低温保存肺の移植に関する研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"微弱磁場環境下・不凍物質添加低温保存肺の移植に関する研究"},{"subitem_title":"Subzero lung preservation in a variable magnetic field using anti-freeze protein","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2816"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-04-11"},"publish_date":"2019-04-11","publish_status":"0","recid":"44358","relation_version_is_last":true,"title":["微弱磁場環境下・不凍物質添加低温保存肺の移植に関する研究"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:03:16.540288+00:00"}