{"created":"2023-07-27T06:51:06.790101+00:00","id":44386,"links":{},"metadata":{"_buckets":{"deposit":"992f4fdc-96c6-4adc-afbb-4242a2a90f3c"},"_deposit":{"created_by":18,"id":"44386","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"44386"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00044386","sets":["2812:2813:2823"]},"author_link":["75714","75713"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-05-09","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2009-2010","bibliographic_titles":[{"bibliographic_title":"平成22(2010)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2010 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"我々が開発したラット専用光干渉断層計によってラット視神経挫滅モデルの網膜神経線維層厚の経時的変化を調べた。その結果、光干渉断層計による計測値の再現性は良好であり、組織切片での計測値と良好な相関がみられた。さらに、10回加算平均と網膜層厚自動計測プログラムを導入し、エンドセリン硝子体内投与モデルにおいて投与後に網膜内層厚が減少しそれに続いて網膜神経線維層厚が減少することを明らかにした。","subitem_description_type":"Abstract"},{"subitem_description":"We examined the changes of the thickness of retinal nerve fiber layer in rat eyes after optic nerve crush by our optical coherence tomography which was optimized to rat eyes. The thickness value measured by the optical coherence tomography showed good repeatability and reproducibility, and was well correlated with that measured by histology. After introduction of multiple scan averaging and an auto-segmentation program, we disclosed that the thickness of the retinal nerve fiber layer decreases following the decrease in the thickness of the inner retinal layer in rat eyes after an intravitreal injection of endothelin-1.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"出典：研究課題「超高解像度光干渉断層計による緑内障関連動物モデルの視神経傷害の生体内定量的評価」課題番号20592035\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-20592035/20592035seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院眼科","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00050728","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=20291370"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=20291370","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20592035/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20592035/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-20592035/20592035seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-20592035/20592035seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-05-14"}],"displaytype":"detail","filename":"HO-PR-HIGASHIDE-T-kaken 2011-4p.pdf","filesize":[{"value":"226.1 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-HIGASHIDE-T-kaken 2011-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/44386/files/HO-PR-HIGASHIDE-T-kaken 2011-4p.pdf"},"version_id":"177ba663-4e74-40bf-930a-981e14400872"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"超高解像度光干渉断層計による緑内障関連動物モデルの視神経傷害の生体内定量的評価","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"超高解像度光干渉断層計による緑内障関連動物モデルの視神経傷害の生体内定量的評価"},{"subitem_title":"In vivo quantitative evaluation of optic nerve damage in animal models related to glaucoma by a ultrahigh-resolution optical coherence tomography","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2823"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-05-14"},"publish_date":"2018-05-14","publish_status":"0","recid":"44386","relation_version_is_last":true,"title":["超高解像度光干渉断層計による緑内障関連動物モデルの視神経傷害の生体内定量的評価"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:17:57.995452+00:00"}