{"created":"2023-07-27T06:51:09.526632+00:00","id":44450,"links":{},"metadata":{"_buckets":{"deposit":"a432b1b0-b5d0-4157-b0c9-1cb5d7b23688"},"_deposit":{"created_by":18,"id":"44450","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"44450"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00044450","sets":["2812:2813:2821"]},"author_link":["76125","62374"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-06-08","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2011-2012","bibliographic_titles":[{"bibliographic_title":"平成24(2012)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2012 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"エキソソームは直径数10nm の細胞外分泌小胞であり、新たな細胞間情報伝達分子として注目されている。本研究課題では子宮内膜癌細胞と子宮内膜間質細胞とのエキソソームを介した情報伝達機構につき検討し、内膜癌細胞から内膜間質細胞へとエキソソームを介した機能性small RNA の受け渡しが証明された。子宮内膜癌細胞は、エキソソーム内RNA の授受を介して内膜間質細胞の遺伝子発現を制御している可能性が示唆された。","subitem_description_type":"Abstract"},{"subitem_description":"Exosomes are small membrane vesicles containing various RNAs. Recent evidence suggests that human cells communicate with each other by exchanging exosomes. We found that endometrial cancer cells transmit gene regulatory small RNAs to endometrial fibroblasts using exosomes as vehicles. The results indicate a novel cell-to-cell communication between cancer cells and stromal cells via exosome transfer.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:23791819, 研究期間(年度):2011-2012","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「エキソソームによる子宮内膜の細胞間情報伝達の分子機構と内膜癌化に関する基礎研究」課題番号23791819\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-23791819/23791819seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域保健学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00050792","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学医薬保健研究域保健学系"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=20397219"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=20397219","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23791819/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23791819/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-23791819/23791819seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-23791819/23791819seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-05-21"}],"displaytype":"detail","filename":"ME-PR-MAIDA-Y-kaken 2013-4p.pdf","filesize":[{"value":"893.1 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-MAIDA-Y-kaken 2013-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/44450/files/ME-PR-MAIDA-Y-kaken 2013-4p.pdf"},"version_id":"615df676-bea6-4ded-abdb-7ba90388cac9"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"エキソソームによる子宮内膜の細胞間情報伝達の分子機構と内膜癌化に関する基礎研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"エキソソームによる子宮内膜の細胞間情報伝達の分子機構と内膜癌化に関する基礎研究"},{"subitem_title":"Cell-to-cell communication via exosome transfer in endometrial cancer","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2821"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-05-21"},"publish_date":"2018-05-21","publish_status":"0","recid":"44450","relation_version_is_last":true,"title":["エキソソームによる子宮内膜の細胞間情報伝達の分子機構と内膜癌化に関する基礎研究"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:41:35.611729+00:00"}