{"created":"2023-07-27T06:51:10.192671+00:00","id":44468,"links":{},"metadata":{"_buckets":{"deposit":"29708e92-86f2-4cbe-bf02-0508580169d5"},"_deposit":{"created_by":18,"id":"44468","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"44468"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00044468","sets":["2812:2813:2820"]},"author_link":["655","76147"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-05-20","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2012-08-31 - 2014-03-31","bibliographic_titles":[{"bibliographic_title":"平成25(2013)年度 科学研究費補助金 研究活動スタート支援 研究成果報告書"},{"bibliographic_title":"2013 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"細胞接着分子を介した造精細胞とセルトリ細胞の相互作用は精子形成に重要な役割を持つ。特に、造精細胞に発現する細胞接着分子 Cadm1は精子形成に必須である。最近我々は、Cadm1と結合するアダプター蛋白質としてMpp6を見いだした。ウエスタンブロット法および免疫組織化学により精巣におけるMpp6の発現と局在を明らかにした。また、免疫沈降によりCadm1とMpp6の相互作用を確認し、さらにMpp6と相互作用する新規分子を複数同定した。","subitem_description_type":"Abstract"},{"subitem_description":"The interaction of germ cells and sertoli cells through cell adhesion molecules is important in spermatogenesis. Cell adhesion molecule-1 (Cadm1), which is expressed in germ cells, is essential for spermatogenesis. Recently we found out Mpp6 as an adopter protein which binds Cadm1. Using Western blot analysis and immunohistochemistry, we revealed the expression and localization of Mpp6 in the mouse testis. Moreover, we confirmed the interaction of Cadm1 and Mpp6 by immunoprecipitation and also identified several new molecules which interact with Mpp6.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:24890074, 研究期間(年度):2012-08-31 - 2014-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：「細胞接着分子による精子形成調節の分子ネットワークの解明」研究成果報告書　課題番号24890074\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-24890074/24890074seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00050810","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学医薬保健研究域医学系"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=80638304"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=80638304","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24890074/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24890074/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-24890074/24890074seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-24890074/24890074seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-05-21"}],"displaytype":"detail","filename":"ME-PR-NAKATA-H-kaken 2014-4p.pdf","filesize":[{"value":"174.9 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-NAKATA-H-kaken 2014-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/44468/files/ME-PR-NAKATA-H-kaken 2014-4p.pdf"},"version_id":"266fe665-c3cc-4f4f-abdf-ab6714c322c3"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"細胞接着分子による精子形成調節の分子ネットワークの解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"細胞接着分子による精子形成調節の分子ネットワークの解明"},{"subitem_title":"Study on the molecular networks in the regulation of mouse spermatogenesis by cell a dhesion molecules","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2820"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-05-21"},"publish_date":"2018-05-21","publish_status":"0","recid":"44468","relation_version_is_last":true,"title":["細胞接着分子による精子形成調節の分子ネットワークの解明"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T09:19:42.583986+00:00"}