{"created":"2023-07-27T06:51:14.700379+00:00","id":44594,"links":{},"metadata":{"_buckets":{"deposit":"0e3e9350-e4fa-445b-8343-b246a48ff371"},"_deposit":{"created_by":18,"id":"44594","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"44594"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00044594","sets":["2812:2813:2817"]},"author_link":["76680","76681"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-04-06","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2015-04-01 - 2017-03-31","bibliographic_titles":[{"bibliographic_title":"平成28(2016)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2016 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究代表者は、ショウジョウバエ腸管における腸内細菌と宿主の相互作用について解析を進めている。本研究では、ショウジョウバエを完全に無菌化することを試みた。これは、特定の細菌のみを定着させて解析を行なうために必要な重要な技術であるが、これまでに真に無菌のショウジョウバエを確立して数世代にわたって維持することは困難であった。そこで研究代表者は、無菌マウス維持に利用される無菌アイソレータを用い、無菌ショウジョウバエの維持・作成のための方法を確立した。すなわち、完全に微生物フリーのショウジョウバエを安定して飼育することが可能になった。","subitem_description_type":"Abstract"},{"subitem_description":"The intestinal tract is one of the first organs acquired by multicellular organisms in the course of evolution. Because of its essential role in the digestion and absorption of food, its nutritive environment provides an ideal niche for commensal microbes, the effects of which are considered tremendous on hosts. Drosophila melanogaster, an invertebrate model organism, certainly possesses a gut, and its microbes could be used for investigating host-microbe interactions. However, generating and maintaining “germ-free” Drosophila is rather challenging. In this study, we established a solid and perhaps the first method for establishing germ-free flies, using a vinyl isolator and fly food with a specific composition. This germ-free fly technique could provide a pivotal basis for analyzing gnotobiotic Drosophila, which will improve our understanding of evolutionarily conserved host-microbe interactions in the intestine.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:15K18855, 研究期間(年度):2015-04-01 - 2017-03-31","subitem_description_type":"Other"},{"subitem_description":"出典:「ショウジョウバエの腸管において腸内細菌の違いを感知する新規メカニズムの解明」研究成果報告書 課題番号15K18855\n(KAKEN:科学研究費助成事業データベース(国立情報学研究所)) \n(https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-15K18855/15K18855seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域薬学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00050935","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=90613167"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=90613167","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K18855/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K18855/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-15K18855/15K18855seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-15K18855/15K18855seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-06-04"}],"displaytype":"detail","filename":"PH-PR-KURAISHI-T-kaken 2017-5p.pdf","filesize":[{"value":"285.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"PH-PR-KURAISHI-T-kaken 2017-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/44594/files/PH-PR-KURAISHI-T-kaken 2017-5p.pdf"},"version_id":"eaaa5ebf-90b2-4a1d-ba1e-a02439dd3f1d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ショウジョウバエの腸管において腸内細菌の違いを感知する新規メカニズムの解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ショウジョウバエの腸管において腸内細菌の違いを感知する新規メカニズムの解明"},{"subitem_title":"Analysis of host-microbe interction in the gut of Drsoophila melanogaster","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2817"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-06-04"},"publish_date":"2018-06-04","publish_status":"0","recid":"44594","relation_version_is_last":true,"title":["ショウジョウバエの腸管において腸内細菌の違いを感知する新規メカニズムの解明"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T11:36:01.022746+00:00"}