{"created":"2023-07-27T06:51:16.686477+00:00","id":44638,"links":{},"metadata":{"_buckets":{"deposit":"2ec583ea-7575-437e-9f55-0752146c6908"},"_deposit":{"created_by":18,"id":"44638","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"44638"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00044638","sets":["2812:2813:2821"]},"author_link":["76750","88"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-05-29","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2010-2012","bibliographic_titles":[{"bibliographic_title":"平成24(2012)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2012 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ヒトと異なり,ビタミンC (AsA)の生合成能を持つマウスでは,酸化ストレスに対して血漿のAsAや血漿総抗酸化能(TAC)がどのように変化するのか良く分かっていない。そこで,急性,及び,慢性炎症モデルを作成し,血漿のAsAや血漿TACの変化を検討した。その結果,マウスでは,炎症反応により上昇したと考えられる生理的AsA要求量に対して,血漿中AsA濃度や血漿TACを短時間に増加させる可能性が示された。","subitem_description_type":"Abstract"},{"subitem_description":"The changes in plasma ascorbate (AsA) and plasma total antioxidant capacity (TAC) induced by oxidative stress in mouse, which can biosynthesize vitamin C unlike human being, are not fully elucidated. The acute inflammation mouse model and the chronic inflammation mouse model were developed and the change in plasma AsA and plasma TAC were examined using them. The results showed that mouse could increase plasma AsA and plasma TAC against the physiological demand of vitamin C, which was increased by inflammatory reaction, in a short time.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:22590221, 研究期間(年度):2010-2012","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「「ビタミンC生合成能を持つマウス」を用いた酸化ストレスとビタミンC代謝の研究」課題番号22590221\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22590221/22590221seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00050979","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学医薬保健研究域医学系"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=20345630"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=20345630","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22590221/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22590221/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22590221/22590221seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22590221/22590221seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-06-07"}],"displaytype":"detail","filename":"ME-PR-KAMBAYASHI-Y-kaken 2013-6p.pdf","filesize":[{"value":"541.6 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-KAMBAYASHI-Y-kaken 2013-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/44638/files/ME-PR-KAMBAYASHI-Y-kaken 2013-6p.pdf"},"version_id":"321c4be3-b890-42b0-87ad-d38433e89b74"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"「ビタミンC生合成能を持つマウス」を用いた酸化ストレスとビタミンC代謝の研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"「ビタミンC生合成能を持つマウス」を用いた酸化ストレスとビタミンC代謝の研究"},{"subitem_title":"Study on oxidative stress and the metabolism of vitamin C using \"mouse having biosynthetic capability vitamin C\"","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2821"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-06-07"},"publish_date":"2018-06-07","publish_status":"0","recid":"44638","relation_version_is_last":true,"title":["「ビタミンC生合成能を持つマウス」を用いた酸化ストレスとビタミンC代謝の研究"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:41:19.865539+00:00"}