{"created":"2023-07-27T06:51:21.723112+00:00","id":44753,"links":{},"metadata":{"_buckets":{"deposit":"e61a4918-0b69-42de-8f94-89193c063af1"},"_deposit":{"created_by":18,"id":"44753","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"44753"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00044753","sets":["2812:2813:2821"]},"author_link":["77187","294"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-05-20","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2010-2012","bibliographic_titles":[{"bibliographic_title":"平成24(2012)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2012 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"免疫不全患者における下痢症の原因原虫として深刻な病害をもたらすクリプトスポリジウム症を効果的に治療可能な薬剤シーズを見いだすことを目的に、候補化合物による抗クリプトスポリジウム効果スクリーニング方法を培養細胞感染モデルの利用により確立した。これにより、アデノシンアナログの一部に明らかなクリプトスポリジウムの増殖抑制効果を見いだし、また、類似化合物である既存抗がん剤の一部に同様の効果を確認した。","subitem_description_type":"Abstract"},{"subitem_description":"Due to the lack of effective chemotherapy, severe cryptosporidiosis especially seen in immune-compromised host is often fetal. To explore drug seeds for the opportunistic infection, a screening method of the drug effect against Cryptosporidiumparvum in a cell culture model was successfully developed. Using the assessment procedure, anti-cryptosporidal efficacy was confirmed in a part of adenosine analogues, including anti-cancer drugs used in clinical sites.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:22590378, 研究期間(年度):2010-2012","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「クリプトスポリジウム症の効果的な治療に関する研究」課題番号22590378\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22590378/22590378seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学先進予防医学研究センター","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00051094","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学先進予防医学研究センター"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=30338024"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=30338024","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22590378/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22590378/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22590378/22590378seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22590378/22590378seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-06-18"}],"displaytype":"detail","filename":"ME-PR-TOKORO-S-kaken 2013-4p.pdf","filesize":[{"value":"627.5 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-TOKORO-S-kaken 2013-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/44753/files/ME-PR-TOKORO-S-kaken 2013-4p.pdf"},"version_id":"a5536665-0d1d-41f9-a41f-f64358584e8f"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"クリプトスポリジウム症の効果的な治療に関する研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"クリプトスポリジウム症の効果的な治療に関する研究"},{"subitem_title":"Study to explore drug seeds for cryptosporidiosis","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2821"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-06-18"},"publish_date":"2018-06-18","publish_status":"0","recid":"44753","relation_version_is_last":true,"title":["クリプトスポリジウム症の効果的な治療に関する研究"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:37:31.321240+00:00"}