{"created":"2023-07-27T06:51:23.089685+00:00","id":44788,"links":{},"metadata":{"_buckets":{"deposit":"88e0ff1f-975a-488e-975a-2c5cc6bf70d7"},"_deposit":{"created_by":18,"id":"44788","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"44788"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00044788","sets":["2812:2813:2823"]},"author_link":["23691","44"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-05-19","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2008-2010","bibliographic_titles":[{"bibliographic_title":"平成22(2010)年度 科学研究費補助金 基盤研究(B) 研究成果報告書"},{"bibliographic_title":"2010 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"アレルギー性疾患の発症におけるRSウイルスによる感染の役割を解明し、分子遺伝マーカーを同定することによって予防法を開発することを目的とした。動物実験と分子疫学によって、その分子遺伝マーカーとして、Th2サイトカイン、LR4とCD14が同定された。RSウイルス由来のS糖タンパク遺伝子を用いたDNAワクチンは、この活性を抑制することによってアレルギー予防につながることが見出され、その有効性が示された。","subitem_description_type":"Abstract"},{"subitem_description":"This study aimed to clarify the involvement of RS virus in allergic diseases and develop preventive methods by determining the molecular and genetic marker in it. Animal experiments and molecular epidemiology determined Th2 cytokines, LR4 and CD4 as the markers. DNA vaccine containing S glycoprotein gene was found to lead to the inactivation of the markers, subsequently resulting in the efficient preventive agents.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:20390170, 研究期間(年度):2008-2010","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「RSウイルス感染によるアレルギー発症における分子遺伝子マーカーの同定と予防法」課題番号20390170\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-20390170/20390170seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00051127","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=30231476"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=30231476","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20390170/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20390170/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-20390170/20390170seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-20390170/20390170seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-06-21"}],"displaytype":"detail","filename":"ME-PR-NAKAMURA-H-kaken 2011-6p.pdf","filesize":[{"value":"253.9 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-NAKAMURA-H-kaken 2011-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/44788/files/ME-PR-NAKAMURA-H-kaken 2011-6p.pdf"},"version_id":"a27827de-4926-446c-96f3-eaffe26748ad"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"RSウイルス感染によるアレルギー発症における分子遺伝子マーカーの同定と予防法","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"RSウイルス感染によるアレルギー発症における分子遺伝子マーカーの同定と予防法"},{"subitem_title":"Determination and molecular and genetic marker in the allergy produced by RS virus infection and its prevention","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2823"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-06-21"},"publish_date":"2018-06-21","publish_status":"0","recid":"44788","relation_version_is_last":true,"title":["RSウイルス感染によるアレルギー発症における分子遺伝子マーカーの同定と予防法"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:17:25.223007+00:00"}