{"created":"2023-07-27T06:51:28.243152+00:00","id":44906,"links":{},"metadata":{"_buckets":{"deposit":"9c3a7589-008c-47f7-9d53-16b93f393ac7"},"_deposit":{"created_by":18,"id":"44906","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"44906"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00044906","sets":["1132:1133:1134"]},"author_link":["75999","77512","77510","77513","77508","77511","10713","77505","77506","77507"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"114","bibliographicPageStart":"112","bibliographicVolumeNumber":"40","bibliographic_titles":[{"bibliographic_title":"日本心臓血管外科学会雑誌"},{"bibliographic_title":"Japanese Journal of Cardiovascular Surgery","bibliographic_titleLang":"en"}]}]},"item_4_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kato, Hiroki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yashiki, Noriyoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Iino, Kenji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tomita, Shigeyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Watanabe, Go"}],"nameIdentifiers":[{},{}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Anticoagulation management in cardiac surgery can be difficult in patients with heparin-induced thrombocytopenia (HIT). We report a patient who underwent reoperation of cardiopulmonary bypass (CPB) using argatroban in combination with nafamostat mesilate. A bolus of 0.25 mg/kg argatroban was administered, followed by continuous infusion of 5-10 μg/kg/min argatroban and 100 mg/h nafamostat mesilate. No complications such as thrombosis were observed during either CPB or the perioperative period. Although we used argatroban and nafamostat mesilate, which has a shorter half-life than argatroban, the anticoagulant effect was prolonged, and the patient had an uneventful postoperative course despite requiring substantial blood transfusion.","subitem_description_type":"Abstract"},{"subitem_description":"へパリン起因性血小板減少症（HIT）を合併した症例に対する心臓手術のさいには，抗凝固管理が重要となる．今回我々はアルガトロバンとメシル酸ナファモスタットを併用した人工心肺下再手術を経験した．今回，アルガトロバンは0.25 mg/kgのbolus投与と5～10 μg/kg/minの持続投与，またメシル酸ナファモスタットは100 mg/hで使用した．人工心肺中や周術期に血栓症などの合併症は認めなかった．アルガトロバンとさらに半減期の短いメシル酸ナファモスタットを使用したにもかかわらず，抗凝固作用が遷延し多量の輸血を要することとなったが術後経過は良好であった．","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_4_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00051245","subitem_identifier_reg_type":"JaLC"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本心臓血管外科学会 = The Japanese Society for Cardiovascular Surgery"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.4326/jjcvs.40.112","subitem_relation_type_select":"DOI"}}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://www.jstage.jst.go.jp/browse/jjcvs/-char/ja/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.jstage.jst.go.jp/browse/jjcvs/-char/ja/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"http://jscvs.umin.ac.jp/index.html"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://jscvs.umin.ac.jp/index.html","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright © 日本心臓血管外科学会 The Japanese Society for Cardiovascular Surgery"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00193284","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0285-1474","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"加藤, 寛城"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"矢鋪, 憲功"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"飯野, 賢治"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"富田, 重之"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"渡辺, 剛"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-06-28"}],"displaytype":"detail","filename":"ME-PR-WATANABE-G-112.pdf","filesize":[{"value":"363.9 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-WATANABE-G-112.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/44906/files/ME-PR-WATANABE-G-112.pdf"},"version_id":"a671eba3-c62e-4079-8bcd-72b5686f29fe"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"へパリン起因性血小板減少症を合併した僧帽弁位人工弁周囲逆流に対する再手術の1例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"へパリン起因性血小板減少症を合併した僧帽弁位人工弁周囲逆流に対する再手術の1例"},{"subitem_title":"A Case of Re-operation for Paravalvular Leakage after Mitral Valve Replacement Complicated by Heparin-Induced Thrombocytopenia","subitem_title_language":"en"}]},"item_type_id":"4","owner":"18","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-06-28"},"publish_date":"2018-06-28","publish_status":"0","recid":"44906","relation_version_is_last":true,"title":["へパリン起因性血小板減少症を合併した僧帽弁位人工弁周囲逆流に対する再手術の1例"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T17:01:41.764034+00:00"}