{"created":"2023-07-27T06:51:39.859464+00:00","id":45171,"links":{},"metadata":{"_buckets":{"deposit":"14ab5d71-4d74-4fc0-8a86-3c29f497e0c0"},"_deposit":{"created_by":18,"id":"45171","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"45171"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00045171","sets":["2812:2813:2815"]},"author_link":["2569","24869"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-06-17","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2016-04-01 - 2019-03-31","bibliographic_titles":[{"bibliographic_title":"平成30(2018)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2018 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{},{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"自閉症スペクトラム障害(ASD)は社会性の障害を主とする発達障害である。共感とは他者と内面を分かち合う事であるが、ASDでは共感性に欠ける。Mismatch field(MMF)は話者が聞き手の注意を促すために発する声に対する脳の反応を脳磁図で計測したものであり社会性の指標となる。我々は今回10名のASD者にオキシトシン(OT)を8-10週間にわたり、MMFの変化を測定するとともに質問紙法(EQ)により行動面から共感性の変化を評価した。結果、OT長期投与中にはMMFの振幅の変化と、EQのスコアの変化に有意な正の相関が認められた。一方、長期投与終了後の評価にはこのような関係は認められなかった。 ","subitem_description_type":"Abstract"},{"subitem_description":"Autism spectrum disorders (ASDs) are neurodevelopmental conditions with impairments in social communica- tion and interaction. Empathy is the ability to understand and share another person's inner life, and it is an essential process in social cognition, which is deficient in ASD. The mismatch field (MMF) has been used as a neurophysiological marker for the automatic detection of changes in auditory stimuli. In the present study, we focused on long-term changes in MMF evoked by an empathic voice and changes in the empathy quotient (EQ) in ASD during an 8-week clinical trial using oxytocin (OT). Ten males with ASD without intellectual disability participated in this pilot study. The results demonstrated a significant positive correlation between the change in the MMF amplitude in the auditory cortex and the change in the EQ score during the 8-week clinical trial, whereas no significant change was observed in the MMF amplitude or EQ score after the administration period of OT. ","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:16K19756, 研究期間(年度):2016-04-01 - 2019-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「オキシトシン長期投与による社会性の変化: 脳磁図を用いた検討」課題番号16K19756\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-16K19756/16K19756seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00051510","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学附属病院神経科精神科"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=80645127"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=80645127","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K19756/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K19756/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-16K19756/16K19756seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-16K19756/16K19756seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-04-24"}],"displaytype":"detail","filename":"HO-PR-HIROSAWA-T-kaken 2019-4p.pdf","filesize":[{"value":"116.5 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-HIROSAWA-T-kaken 2019-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/45171/files/HO-PR-HIROSAWA-T-kaken 2019-4p.pdf"},"version_id":"132aa2cc-0458-4b45-90e4-e0f493ff529b"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"オキシトシン長期投与による社会性の変化: 脳磁図を用いた検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"オキシトシン長期投与による社会性の変化: 脳磁図を用いた検討"},{"subitem_title":"Longitudinal changes in sociality after long-term administration of oxytocin - MEG study","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2815"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-04-24"},"publish_date":"2020-04-24","publish_status":"0","recid":"45171","relation_version_is_last":true,"title":["オキシトシン長期投与による社会性の変化: 脳磁図を用いた検討"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:35:44.463250+00:00"}