{"created":"2023-07-27T06:51:41.187868+00:00","id":45203,"links":{},"metadata":{"_buckets":{"deposit":"5e10af1d-9794-4ec0-89e0-b3d3d28e9e49"},"_deposit":{"created_by":18,"id":"45203","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"45203"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00045203","sets":["2812:2813:2821"]},"author_link":["330","70238"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-04-07","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2010-2012","bibliographic_titles":[{"bibliographic_title":"平成24(2012)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2012 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ヒト検体を用いた,バイオマーカー検索に関しては,収集した急性腎障害症例の経時的な検体を質量分析計で検討し再現性の高いバイオマーカー候補分子を確認した。また、炎症関連物質の測定を行い、病態や予後と関連する因子を同定した。一方、脂肪由来間葉系細胞による検討では、細胞の多分化能と自己複製能を示した。また、尾静脈より投与した脂肪由来間葉系細胞は腎臓には生着しないものの、腎における抗炎症作用を持つことが示された。バイオマーカーに関しては,特許申請の準備中であり、脂肪由来間葉系細胞に関しては、論文として発表した。","subitem_description_type":"Abstract"},{"subitem_description":"Everal urinary biomarker candidates of acute kidney injury were detected by mass spectrometry. We also detected several urinary biomarker candidates of acute kidney injury by multiple cytokine/chemokine detection methods. In this study, we explored the effects of adipose-derived mesenchymal cells on a mouse model of AKI. The effects of adipose-derived mesenchymal cells were evaluated in AKI mouse model. A lthough, administered adipose-derived mesenchymal cells were tend to home into lung, repeated administration of adipose-derived mesenchymal cells reduced acute tubular necrosis and interstitial macrophage infiltration.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19890082, 研究期間(年度):2010-2012","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00051542","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学附属病院血液浄化療法部"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=50432125"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=50432125","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22590883/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22590883/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22590883/22590883seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22590883/22590883seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-07-06"}],"displaytype":"detail","filename":"HO-PR-FURUICHI-K-kaken 2013-4p.pdf","filesize":[{"value":"618.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-FURUICHI-K-kaken 2013-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/45203/files/HO-PR-FURUICHI-K-kaken 2013-4p.pdf"},"version_id":"8670ff03-c25e-4bde-9d92-1f7a06633d2d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"急性腎障害に対する脂肪由来肝細胞による治療および網羅的バイオマーカーの開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"急性腎障害に対する脂肪由来肝細胞による治療および網羅的バイオマーカーの開発"},{"subitem_title":"Therapeutic approaches of AKI by adipose-derived mesenchymal cells, and urinary biomarker search in AKI","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2821"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-07-06"},"publish_date":"2018-07-06","publish_status":"0","recid":"45203","relation_version_is_last":true,"title":["急性腎障害に対する脂肪由来肝細胞による治療および網羅的バイオマーカーの開発"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T15:41:57.284526+00:00"}