{"created":"2023-07-27T06:51:42.937013+00:00","id":45242,"links":{},"metadata":{"_buckets":{"deposit":"0eea2a06-28da-4b41-b52c-0a5757f83ef2"},"_deposit":{"created_by":18,"id":"45242","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"45242"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00045242","sets":["2812:2813:2825"]},"author_link":["2011","21455"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2007-2008","bibliographic_titles":[{"bibliographic_title":"平成20(2008)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2008 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kondo, Satoru"}],"nameIdentifiers":[{"nameIdentifier":"21455","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70436822","nameIdentifierScheme":"金沢大学研究者情報","nameIdentifierURI":"http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=70436822"},{"nameIdentifier":"70436822","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000070436822"}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"MDM2は癌抑制遺伝子p53分解を促進し、この過剰発現は各種の悪性腫瘍において認められる。MDM2プロモーターに存在する一塩基多型(SNP)が、p53遺伝子異常を伴うLi-Fraumeni症候群患者における悪性腫瘍の発生年齢に有意に影響を与えることが近年報告された。本研究では上咽頭癌で先述のSNPは上咽頭がん発症リスクに関与しないか検証し、また上咽頭がんの発症、病態、予後に影響を与えるかについて検証した。更に横断的に他の頭頸部癌患者でも解析を行った。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19791198, 研究期間(年度):2007-2008","subitem_description_type":"Other"},{"subitem_description":"出典：「MDM2プロモーター遺伝子多型の上咽頭がんに対する関与」研究成果報告書　課題番号19791198\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19791198/19791198seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00051581","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学附属病院耳鼻咽喉科・頭頸部外科"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=70436822"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=70436822","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19791198/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19791198/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19791198/19791198seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19791198/19791198seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"近藤, 悟"}],"nameIdentifiers":[{"nameIdentifier":"2011","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70436822","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=70436822"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-07-09"}],"displaytype":"detail","filename":"HO-PR-KONDO-S-kaken 2009-4p.pdf","filesize":[{"value":"214.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-KONDO-S-kaken 2009-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/45242/files/HO-PR-KONDO-S-kaken 2009-4p.pdf"},"version_id":"49b08564-9522-464e-8851-1dbb01eed629"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"MDM2プロモーター遺伝子多型の上咽頭がんに対する関与","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"MDM2プロモーター遺伝子多型の上咽頭がんに対する関与"},{"subitem_title":"Association of single nucleotide polymorphism of MDM2 promoter in nasopharyngeal carcinoma patients","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2825"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-07-09"},"publish_date":"2018-07-09","publish_status":"0","recid":"45242","relation_version_is_last":true,"title":["MDM2プロモーター遺伝子多型の上咽頭がんに対する関与"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-07-01T06:10:03.501975+00:00"}