{"created":"2023-07-27T06:51:48.209476+00:00","id":45370,"links":{},"metadata":{"_buckets":{"deposit":"46e3e373-bf7c-43dd-9198-50373d45fe91"},"_deposit":{"created_by":18,"id":"45370","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"45370"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00045370","sets":["2812:2813:2821"]},"author_link":["2188","78881"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-05-20","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2011-2012","bibliographic_titles":[{"bibliographic_title":"平成24(2012)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2012 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本研究ではアルツハイマー病(AD)治療効果が期待される、植物由来の天然ポリフェノールの安全性および忍容性を確認することを目的とし、AD患者を対象にポリフェノール経口摂取の安全性、忍容性、代謝動態および認知機能改善効果を評価するための臨床試験を実施した。試験食品を作成し、60歳以上AD患者14名に対して投与を開始した。平成25年5月時点で、試験食品開始後の身体所見、神経学的所見、バイタルサイン、臨床検査の顕著な異常はみとめておらず、ポリフェノール経口摂取の安全性は高いものと予測される。","subitem_description_type":"Abstract"},{"subitem_description":"This study evaluated the safety and tolerability of polyphenols in patients with Alzheimer’s disease. This is a uni-center, double-blind, randomized, placebo-controlled clinical trial of 48 weeks. Primary outcome measure is safety and tolerability of polyphenols. We have started polyphenol capsules administration in 14 patients. No significant adverse events have not been reported by any of the patients due to study treatment until May 2013. Oral administration of polyphenols will appearto be safe in patients with Alzheimer’s disease.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:23790984, 研究期間(年度):2011-2012","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「アルツハイマー病患者におけるポリフェノールの安全性と有効性に関する検討」課題番号23790984\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-23790984/23790984seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00051707","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学医薬保健研究域医学系"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=20584832"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=20584832","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23790984/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23790984/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-23790984/23790984seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-23790984/23790984seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-07-20"}],"displaytype":"detail","filename":"HO-PR-SHINOHARA-M-kaken 2013-4p.pdf","filesize":[{"value":"368.3 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-SHINOHARA-M-kaken 2013-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/45370/files/HO-PR-SHINOHARA-M-kaken 2013-4p.pdf"},"version_id":"2eb4c9dc-f019-42c3-a391-a58506b6b35f"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"アルツハイマー病患者におけるポリフェノールの安全性と有効性に関する検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"アルツハイマー病患者におけるポリフェノールの安全性と有効性に関する検討"},{"subitem_title":"Safety and efficacy of polyphenols in patients with Alzheimer's disease","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2821"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-07-20"},"publish_date":"2018-07-20","publish_status":"0","recid":"45370","relation_version_is_last":true,"title":["アルツハイマー病患者におけるポリフェノールの安全性と有効性に関する検討"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:35:02.623700+00:00"}