{"created":"2023-07-27T06:51:49.355631+00:00","id":45396,"links":{},"metadata":{"_buckets":{"deposit":"b1d3a4ac-7359-4df1-8ead-a160a057928b"},"_deposit":{"created_by":18,"id":"45396","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"45396"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00045396","sets":["2812:2813:2818"]},"author_link":["78915","405"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-06-13","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2013-04-01 - 2016-03-31","bibliographic_titles":[{"bibliographic_title":"平成27(2015)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2015 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"IVR技術を利用した特異的、効率的、非侵襲的delivery systemを開発するため、血管作動性物質による血管透過性の制御機能について検討した。光音響イメージングにてインドシアニングリーン（ICG）の動態を確認することが可能であり、ICGが細胞内に取り込まれていることも確認できた。また、血管透過性が亢進した状態ではエバンスブルーの組織内蓄積が増強し、血管透過性が低下した状態ではICGによる光音響イメージングシグナルが低下した。","subitem_description_type":"Abstract"},{"subitem_description":"To develop specific, effective and non-invasive delivery system using IVR technology, we investigated the relationship of vasoactive substances to vascular permeability. By photoacoustic imaging, it was possible to confirm the kinetics of indocyanine green (ICG) and ICG uptake into the cells. In addition, the tissue accumulation of Evans blue was enhanced in the state of increased vascular permeability, and the signal of a photoacoustic imaging by ICG was reduced in the state of decreased vascular permeability.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:25461872, 研究期間(年度):2013-04-01 - 2016-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「ミクロ粒子の経動脈的注入における粒子と溶出薬剤の動態とその制御に関する実験的研究」課題番号25461872\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25461872/25461872seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00051733","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=30401920"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=30401920","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25461872/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25461872/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25461872/25461872seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25461872/25461872seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-07-20"}],"displaytype":"detail","filename":"ME-PR-KODA-W-kaken 2016-5p.pdf","filesize":[{"value":"527.2 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-KODA-W-kaken 2016-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/45396/files/ME-PR-KODA-W-kaken 2016-5p.pdf"},"version_id":"6778dd25-e896-4b92-9cac-46d6201e7053"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ミクロ粒子の経動脈的注入における粒子と溶出薬剤の動態とその制御に関する実験的研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ミクロ粒子の経動脈的注入における粒子と溶出薬剤の動態とその制御に関する実験的研究"},{"subitem_title":"Experimental study on control of the drug distribution in transarterial infusion","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2818"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-07-20"},"publish_date":"2018-07-20","publish_status":"0","recid":"45396","relation_version_is_last":true,"title":["ミクロ粒子の経動脈的注入における粒子と溶出薬剤の動態とその制御に関する実験的研究"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T10:55:01.363897+00:00"}