{"created":"2023-07-27T06:51:56.957176+00:00","id":45586,"links":{},"metadata":{"_buckets":{"deposit":"f483d0c0-0aec-4a34-8816-6f988ab5258d"},"_deposit":{"created_by":18,"id":"45586","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"45586"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00045586","sets":["2812:2813:2820"]},"author_link":["2410","13493"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-06-06","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2012-04-01 - 2014-03-31","bibliographic_titles":[{"bibliographic_title":"平成25(2013)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2013 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{},{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"外界からの情報を正確に感知し、適切に応答することは、動物の生存・子孫維持に極めて重要である。本研究者は比較的シンプルな構造からなる昆虫の嗅覚系に着目し、性フェロモン受容が行動を制御する仕組みの解明に取り組んできた。本研究ではカイコガの脳より神経活動依存的に発現量が増加する新規な遺伝子としてHr38を同定し、これがカイコガ・ショウジョウバエの脳において神経活動のマーカーとして利用できることを見出し、異性の匂いに応答する細胞の包括的同定に成功した。さらに遺伝子組換え昆虫を用いて神経活動の起こった神経細胞特異的にGFPなどのレポーター遺伝子を発現する昆虫の作成を試みた。","subitem_description_type":"Abstract"},{"subitem_description":"Many insects exhibit stereotypic instinctive behavior, but the underlying neural mechanisms are not well understood due to difficulties in detecting brain activity in freely-moving animals. Immediate early genes (IEGs) whose expression is transiently and rapidly upregulated upon neural activity are powerful tools for detecting behavior-related neural activity. In the present study, I identified Hr38 as a novel IEG that is transiently expressed in the male silkmoth, Bombyx mori, by female odor stimulation. Using Hr38 expression as an indicator of neural activity, I mapped comprehensive activity patterns of the silkmoth brain in response to female sex pheromones. I found that Hr38 can also be used as a neural activity marker in the fly, Drosophila melanogaster. Using Hr38, I constructed a neural activity map of the fly brain in response to female stimulation. In adddition, I established transgenic insects whose active neurons can be visualized with GFP, using Hr38 expression as tools.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:24780047, 研究期間(年度):2012-04-01 - 2014-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「新規な神経活動依存的遺伝子を用いた昆虫の性フェロモン神経回路の可視化と機能解析」課題番号24780047\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-24780047/24780047seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00051923","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学理工研究域生命理工学系"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=90532309"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=90532309","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24780047/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24780047/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-24780047/24780047seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-24780047/24780047seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-17"}],"displaytype":"detail","filename":"SC-PR-KIYA-T-kaken 2014-6p.pdf","filesize":[{"value":"301.3 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"SC-PR-KIYA-T-kaken 2014-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/45586/files/SC-PR-KIYA-T-kaken 2014-6p.pdf"},"version_id":"55251ba7-4d9c-4fba-a029-089e7928c32a"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"新規な神経活動依存的遺伝子を用いた昆虫の性フェロモン神経回路の可視化と機能解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"新規な神経活動依存的遺伝子を用いた昆虫の性フェロモン神経回路の可視化と機能解析"},{"subitem_title":"Visualization and analysis of sex pheromone neural circuits in isects using a novel immediate early gene","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2820"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-08-17"},"publish_date":"2018-08-17","publish_status":"0","recid":"45586","relation_version_is_last":true,"title":["新規な神経活動依存的遺伝子を用いた昆虫の性フェロモン神経回路の可視化と機能解析"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T09:17:58.320867+00:00"}