@article{oai:kanazawa-u.repo.nii.ac.jp:00045603,
 author = {北島, 友香 and 粟野, 雅代 and 島田, 啓子 and Kitajima, Yuka and Awano, Masayo and Shimada, Keiko},
 issue = {1},
 journal = {Journal of wellness and health care, Journal of wellness and health care},
 month = {Aug},
 note = {Purpose: This study was performed to examine the utility of a portable ultrasound diagnostic imaging device to evaluate mammary gland development over the course of pregnancy.
Methods: Eight women with normal pregnancies participated in the study. The portable ultrasound diagnostic imaging device used was a Vscan Dual Probe (GE Healthcare, Tokyo, Japan). For the measurement area, the probe was placed at the 10:３0 position in C area of the right breast, with the edge of the probe at a position corresponding to the edge of the nipple. The subjects lay in the supine position with adjustment using a towel so that the breast was in a natural shape. Mammary gland thickness and imaging appearances were assessed longitudinally three times (once in each of the first, second, and third trimesters of pregnancy).
Results: Mammary gland thickness increased over the course of pregnancy in all subjects. The mammary gland thickness showed a significant increase in the second and third trimesters of pregnancy compared to the first trimester (p< 0.01). In five of eight subjects (6２.5%), we found changes in imaging findings associated with the progress of pregnancy. From the first through the second trimester, the mammary glands became hypoechoic, and the subcutaneous fat thinned. Imaging findings were not uniform and showed variations between subjects.
Discussion: This study suggested that the portable ultrasound diagnostic imaging device is useful for evaluation of mammary gland development associated with the progress of pregnancy based on mammary gland thickness. However, it is difficult to evaluate mammary gland development by imaging findings. It is preferable to use changes, such as “the mammary glands became hypoechoic” and “the subcutaneous fat thinned,” as references for evaluating mammary development., 【目的】本研究は、乳腺の妊娠経過に伴う発育評価における携帯型超音波画像診断装置の
有用性を検討することを目的とする。
【方法】正常な経過をたどる妊婦 8 名を対象とした。携帯型超音波画像診断装置は、Vscan Dual Probe（GE ヘルスケア・ジャパン）を使用し、撮影部位は、右乳房 C 領域の10 時 ３0 分の位置とした。対象は仰臥位とし、乳房が自然な形となるようタオルを用いて調整し、プローブは、プローブの辺縁と乳頭の辺縁が一致する位置に当てた。妊娠初期、妊娠中期、妊娠後期の計 ３ 回縦断的に撮影し、乳腺の厚さと画像所見を観察した。【結果】すべての対象者において妊娠経過に伴い乳腺の厚さが増した。妊娠初期に比べて
妊娠中期および妊娠後期は有意に乳腺の厚みが増していた（p＜0.01）。また、対象者 8
名中 5 名（6２.5％）において、妊娠初期から妊娠中期にかけて「乳腺が低エコー像となる」、「脂肪組織が薄くなる」という画像所見の変化が観察できた。画像所見は一様ではなく個
人差が大きかった。
【考察】携帯型超音波画像診断装置は、乳腺の厚さの推移から乳腺の発育を評価することにおいて有用であることが示唆された。画像所見による発育の評価は難しく、乳腺が低エコー像となる」、「脂肪組織が薄くなる」といった画像所見の変化は評価の参考に用いることが望ましい。},
 pages = {9--19},
 title = {Utility of a portable ultrasound diagnostic imaging device to evaluate pregnancy-related mammary gland development},
 volume = {42},
 year = {2018}
}