{"created":"2023-07-27T06:52:16.316512+00:00","id":46078,"links":{},"metadata":{"_buckets":{"deposit":"dcd6b580-1d50-4da0-9758-803f4205c9ba"},"_deposit":{"created_by":18,"id":"46078","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"46078"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00046078","sets":["2812:2813:2821"]},"author_link":["247","79935"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-05-27","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2011-2012","bibliographic_titles":[{"bibliographic_title":"平成24(2012)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2012 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ヒト染色体工学技術を用いることで,神経細胞におけるヒト 15 番染色体の空間的配置と組織特異的遺伝子発現制御機構の解明に取り組んだ。その結果,PWS-IC 領域は活発な遺伝子発現を呈する遺伝子領域をヒト 15 番染色体テリトリーの外にループアウトする機能を持つことを見いだした。これらの結果から,ヒト 15 番染色体上の遺伝子は,染色体の空間的配置によって高度に制御されていることが明らかとなった。","subitem_description_type":"Abstract"},{"subitem_description":"I examined the chromosome territory of a human chromosome 15 in neuronal cells by using the chromosome engineering techniques. Finally, I found that active gene region of 15q11-q13 was looping out from the chromosome 15 territory. From my results, 15q11-q13 locus was highly coordinately regulated by PWS-IC.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:23710215, 研究期間(年度):2011-2012","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「染色体の空間的配置と組織特異的遺伝子発現制御機構の解明」課題番号23710215\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-23710215/23710215seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00052412","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学学際科学実験センター"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=40448311"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=40448311","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23710215/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23710215/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-23710215/23710215seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-23710215/23710215seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-10-12"}],"displaytype":"detail","filename":"FR-PR-HORIIKE-S-kaken 2013-5p.pdf","filesize":[{"value":"186.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"FR-PR-HORIIKE-S-kaken 2013-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/46078/files/FR-PR-HORIIKE-S-kaken 2013-5p.pdf"},"version_id":"2a188c3b-0ebb-4975-bbb3-af2983687696"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"染色体の空間的配置と組織特異的遺伝子発現制御機構の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"染色体の空間的配置と組織特異的遺伝子発現制御機構の解明"},{"subitem_title":"The chromosomal territory influencing the regulation of gene expression in neuronal cells","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2821"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-10-12"},"publish_date":"2018-10-12","publish_status":"0","recid":"46078","relation_version_is_last":true,"title":["染色体の空間的配置と組織特異的遺伝子発現制御機構の解明"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:31:39.435414+00:00"}