{"created":"2023-07-27T06:52:22.883312+00:00","id":46266,"links":{},"metadata":{"_buckets":{"deposit":"c501ddc3-e03a-4ad9-8eb6-a3c9b4e4fddb"},"_deposit":{"created_by":18,"id":"46266","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"46266"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00046266","sets":["2812:2813:2822"]},"author_link":["80169","80168"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-05-29","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2010-2011","bibliographic_titles":[{"bibliographic_title":"平成23(2011)年度 科学研究費補助金若手研究(B) 研究成果報告書"},{"bibliographic_title":"2011 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kitamura, Yoji"}],"nameIdentifiers":[{"nameIdentifier":"80169","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10368483","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=10368483"}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本研究では、新規「放射性金属-八臭素化ポルフィリン錯体」を開発し、腫瘍の新規核医学診断・治療薬剤への応用について検討した。その結果、Octabromotetrakis(4-carboxyphenyl) porphine(OBTCPP)が、診断用核種の111Inで短時間で標識可能なこと、colon26細胞、B16/BL6細胞を移植した担癌マウスにおいて、111In-OBTCPPは投与24時間後、いずれの腫瘍へも約7% dose/gの集積を示すことを見出した。","subitem_description_type":"Abstract"},{"subitem_description":"In this study, a new radiometal-octabromoporphyrines was developed and the possibililty of application for a new nuclear medicine diagnosis and radioisotope therapy agent was examined. As a result, it was found that Octabromotetrakis(4-carboxyphenyl) porphine(OBTCPP) could be radiolabelled by 111In, a radio nuclear for diagnosis, in short times. It was also found that, in tumor bearing mice which transplanted colon26 tumor cell and B16/BL6 tumor cell, 111In-OBTCPP was accumulated in both tumors at about 7% dose/g.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:22791179, 研究期間(年度):2010-2011","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「放射性金属- 八臭素化ポルフィリンを用いた新規核医学診断・治療薬剤の開発と応用」課題番号22791179\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22791179/22791179seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学学際科学実験センターアイソトープ総合研究施設","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00052599","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=10368483"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=10368483","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22791179/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22791179/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22791179/22791179seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22791179/22791179seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"北村, 暘二"}],"nameIdentifiers":[{"nameIdentifier":"80168","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10368483","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=10368483"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-10-26"}],"displaytype":"detail","filename":"AD-PR-KITAMURA-Y-kaken 2012-5p.pdf","filesize":[{"value":"255.3 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"AD-PR-KITAMURA-Y-kaken 2012-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/46266/files/AD-PR-KITAMURA-Y-kaken 2012-5p.pdf"},"version_id":"4ddf18b8-af88-4968-9197-484aee7df687"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"放射性金属- 八臭素化ポルフィリンを用いた新規核医学診断・治療薬剤の開発と応用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"放射性金属- 八臭素化ポルフィリンを用いた新規核医学診断・治療薬剤の開発と応用"},{"subitem_title":"Development and application of radiometal-octabromoporphyrines for a new nuclear medicind diagnosis and radioisotope therapy agent","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2822"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-10-26"},"publish_date":"2018-10-26","publish_status":"0","recid":"46266","relation_version_is_last":true,"title":["放射性金属- 八臭素化ポルフィリンを用いた新規核医学診断・治療薬剤の開発と応用"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-07-01T05:57:48.256838+00:00"}