{"created":"2023-07-27T06:52:32.767924+00:00","id":46538,"links":{},"metadata":{"_buckets":{"deposit":"52a33239-1571-4158-b869-6dcf8fd353b5"},"_deposit":{"created_by":18,"id":"46538","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"46538"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00046538","sets":["2812:2813:2815"]},"author_link":["99","23680"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-05-29","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2015-04-01 - 2019-03-31","bibliographic_titles":[{"bibliographic_title":"平成30(2018)年度 科学研究費補助金 基盤研究(B) 研究成果報告書"},{"bibliographic_title":"2018 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Since 2002, the adverse health effects by herbicides containing dioxins sprayed during the Vietnamese War have been investigated and it was found that dioxins levels of lactating milk of mothers in heavily polluted area were significantly higher than those in the non-polluted area. Since 2008, steroid hormones of mothers and their children have been analyzed and significant positive correlation was shown between cortisol of serum and dioxin of breast milk in mothers.\nDuring the research period on the children cohort, testosterone levels of 5 and 7 years old children in the sprayed area were significantly lower than those in the non-polluted area, respectively.\nWhen cortisol levels of mothers were higher, it was found that 12 % of low birth body weight infants (less than 2,500 g) in heavily polluted area were 3 times higher than 4 % of those in the non-polluted area. From results, dioxins are strongly suspected the main cause of growth retardation of children in the polluted area.","subitem_description_type":"Abstract"},{"subitem_description":"2002年より、ベトナムで枯葉剤に含有されたダイオキシン（DXN）の健康影響調査を始め、撒布地区の母親の母乳中DXNは対照地区より有意に高値であることを明らかにした。2008年より、母子のステロイドホルモンの測定を始め、母親の血清コルチゾールと母乳中DXN濃度との間に正の相関を認めた。\n本研究期間中に、小児のコホート研究で、5歳児・7歳児のテストステロンが汚染地区で有意に低下していることを明らかにした。\nまた、母親のコルチゾールが高い場合に、低体重児（2,500g未満）の出現頻度が、汚染地区では12%と対照地区の4%に対して3倍も高く、DXNが小児の発育に悪影響を与えていることが強く示唆された。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:15H05285, 研究期間(年度):2015-04-01 - 2019-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：「ベトナムのダイオキシンや残留性有機汚染物質の小児ステロイドホルモンへの長期的影響」研究成果報告書　課題番号15H05285\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-15H05285/15H05285seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00052870","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学医薬保健研究域保健学系"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=20167373"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=20167373","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H05285/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H05285/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-15H05285/15H05285seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-15H05285/15H05285seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-04-13"}],"displaytype":"detail","filename":"ME-PR-KIDO-T-kaken 2019-6p.pdf","filesize":[{"value":"256.2 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-KIDO-T-kaken 2019-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/46538/files/ME-PR-KIDO-T-kaken 2019-6p.pdf"},"version_id":"fe5bc0b0-44bc-48c1-8863-cf89c5dbd8e5"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ベトナムのダイオキシンや残留性有機汚染物質の小児ステロイドホルモンへの長期的影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ベトナムのダイオキシンや残留性有機汚染物質の小児ステロイドホルモンへの長期的影響"},{"subitem_title":"Long-term effects on steroid hormone in children by dioxins and persistent organic pollutants in Vietnam","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2815"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-04-13"},"publish_date":"2020-04-13","publish_status":"0","recid":"46538","relation_version_is_last":true,"title":["ベトナムのダイオキシンや残留性有機汚染物質の小児ステロイドホルモンへの長期的影響"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:40:50.983425+00:00"}