{"created":"2023-07-27T06:52:36.135983+00:00","id":46624,"links":{},"metadata":{"_buckets":{"deposit":"af146fc0-3097-4d30-8fb9-bc8c88b6d325"},"_deposit":{"created_by":18,"id":"46624","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"46624"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00046624","sets":["2812:2813:2817"]},"author_link":["81147","81146"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-06-08","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2013-04-01 - 2017-03-31","bibliographic_titles":[{"bibliographic_title":"平成28(2016)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2016 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"血縁構造を除外した集団と除外しない集団で、表現型と環境因子との関連性の結果に違いがあるか、サンプルサイズ、血縁構造化の大きさ、表現型の有病率、易罹病性の遺伝率、リスク環境因子の効果サイズの５つの観点で検証し、血縁構造化の影響を調べた。環境因子と遺伝因子すべての効果は一つの変量、つまり易罹病性に集約されることを考慮し、血縁構造を除外した集団と除外しない集団で、それぞれの易罹病性の分布に違いがあるかｔ検定を行ったところ、有意な差はみられなかったが、家系内に遺伝力がある程度大きく、稀な疾患を想定した限られた条件下でのシミュレーション結果であることも考慮し、今後の更なる詳細な検討は必要である。","subitem_description_type":"Abstract"},{"subitem_description":"We investigated the confounding effect of unadjusted cryptic relatedness among a rural cohort in the relationship between environmental risk factors and quantitative traits interms of sample size, the prevalence, the helitability of liability, the effect size of environmental risk factores. We found a confounding effect of cryptic relatedness in the relationship between quantitative trait and environmnetal risk factors was not negligible.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:25860436, 研究期間(年度):2013-04-01 - 2017-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：「疫学研究における血縁構造化対策ガイドラインの作成」研究成果報告書　課題番号25860436\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25860436/25860436seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院先端医療開発センター","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00052956","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=90535600"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=90535600","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25860436/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25860436/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25860436/25860436seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25860436/25860436seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-12-20"}],"displaytype":"detail","filename":"HO-PR-SHIBATA-K-kaken 2017-4p.pdf","filesize":[{"value":"227.0 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-SHIBATA-K-kaken 2017-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/46624/files/HO-PR-SHIBATA-K-kaken 2017-4p.pdf"},"version_id":"f150afc0-f8ac-4858-851f-6ccef667df12"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"疫学研究における血縁構造化対策ガイドラインの作成","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"疫学研究における血縁構造化対策ガイドラインの作成"},{"subitem_title":"The confounding effect of cryptic relatedness in epidemiology","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2817"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-12-20"},"publish_date":"2018-12-20","publish_status":"0","recid":"46624","relation_version_is_last":true,"title":["疫学研究における血縁構造化対策ガイドラインの作成"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T11:08:23.667740+00:00"}