{"created":"2023-07-27T06:53:47.573491+00:00","id":48651,"links":{},"metadata":{"_buckets":{"deposit":"b172aa94-3fd1-473d-9945-e6748df83103"},"_deposit":{"created_by":18,"id":"48651","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"48651"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00048651","sets":["2812:2813:2824"]},"author_link":["86556","2253"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-04-09","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2007-2009","bibliographic_titles":[{"bibliographic_title":"平成21(2009)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2009 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ヘムオキシゲナーゼ-1(HO-1)およびその代謝産物が血液凝固・線溶系因子の発現を調節し,血液凝固を阻害するかどうか,およびその作用機序をin vitroで検討した.その結果,HO-1およびHO-1代謝産物はp38MAPK およびERK1/2を介して組織因子,プラスミノゲンアクチベーターインヒビタータイプIの発現を抑制,トロンボモジュリンの発現を促進し,血液凝固を阻止する可能性が示された.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19599008, 研究期間(年度):2007-2009","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「ヘムオキシゲナーゼ-1(HO-1)が凝固・線溶系因子の発現調節に果たす役割の解明」課題番号19599008\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19599008/19599008seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00054973","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学医薬保健研究域保健学系"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=10452111"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=10452111","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19599008/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19599008/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19599008/19599008seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19599008/19599008seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-07-22"}],"displaytype":"detail","filename":"ME-PR-SEKIYA-A-kaken 2010-6p.pdf","filesize":[{"value":"480.6 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-SEKIYA-A-kaken 2010-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/48651/files/ME-PR-SEKIYA-A-kaken 2010-6p.pdf"},"version_id":"3a58c711-6862-4abe-bffe-6667af1caaad"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ヘムオキシゲナーゼ-1(HO-1)が凝固・線溶系因子の発現調節に果たす役割の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ヘムオキシゲナーゼ-1(HO-1)が凝固・線溶系因子の発現調節に果たす役割の解明"},{"subitem_title":"The effects of Heme Oxygenase-1 on expression of blood coagulation/fibrinolysis associated proteins","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2824"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-07-22"},"publish_date":"2019-07-22","publish_status":"0","recid":"48651","relation_version_is_last":true,"title":["ヘムオキシゲナーゼ-1(HO-1)が凝固・線溶系因子の発現調節に果たす役割の解明"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:13:09.385875+00:00"}