{"created":"2023-07-27T06:53:50.105192+00:00","id":48812,"links":{},"metadata":{"_buckets":{"deposit":"1a23cb5d-7910-424d-a948-9ce9df47fdde"},"_deposit":{"created_by":18,"id":"48812","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"48812"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00048812","sets":["2812:2813:2817"]},"author_link":["86825","86826"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-06-12","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2014-04-01 - 2017-03-31","bibliographic_titles":[{"bibliographic_title":"平成28(2016)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2016 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本研究では、細胞内の蛋白分解系のエネルギー代謝恒常性維持における役割の統合的理解を目指し、次の3つの未解決課題に取り組んだ。①肥満状態でプロテアソーム機能が低下する機序、②プロテアソーム活性阻害下および飢餓状態での代償的オートファジーのエネルギー代謝における意義とその基質、③骨格筋におけるプロテアソーム機能障害のインスリン感受性における意義","subitem_description_type":"Abstract"},{"subitem_description":"To understand the roles of intracellular proteolytic systems in maintaining energy metabolism homeostasis, the present study addressed the following three unresolved issues. ①Mechanisms underlying proteasome dysfunction in obesity, ②Significance of compensatory autophagy and its substrates under inhibition of proteasome activity and starvation, ③Significance of proteasome dysfunction in skeletal muscle in insulin sensitivity.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:26461329, 研究期間(年度):2014-04-01 - 2017-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：「細胞内蛋白分解系のエネルギー代謝恒常性維持における統合的役割の解明」研究成果報告書　課題番号26461329\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-26461329/26461329seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00055131","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=00324111"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=00324111","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26461329/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26461329/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-26461329/26461329seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-26461329/26461329seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-08"}],"displaytype":"detail","filename":"ME-PR-TAKAMURA-T-kaken 2017-6p.pdf","filesize":[{"value":"189.7 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-TAKAMURA-T-kaken 2017-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/48812/files/ME-PR-TAKAMURA-T-kaken 2017-6p.pdf"},"version_id":"64607b86-cd24-48cb-8eff-6b0dba7f27d1"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"細胞内蛋白分解系のエネルギー代謝恒常性維持における統合的役割の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"細胞内蛋白分解系のエネルギー代謝恒常性維持における統合的役割の解明"},{"subitem_title":"Roles of intracellular proteolytic systems in maintaining energy metabolism homeostasis","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2817"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-08-08"},"publish_date":"2019-08-08","publish_status":"0","recid":"48812","relation_version_is_last":true,"title":["細胞内蛋白分解系のエネルギー代謝恒常性維持における統合的役割の解明"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T11:13:43.637800+00:00"}