{"created":"2023-07-27T06:54:50.984580+00:00","id":50395,"links":{},"metadata":{"_buckets":{"deposit":"8db8ae34-65e2-4afc-b42a-61519a766e05"},"_deposit":{"created_by":18,"id":"50395","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"50395"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00050395","sets":["2812:2813:2825"]},"author_link":["91219","91218"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-05-29","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2007-2008","bibliographic_titles":[{"bibliographic_title":"平成20(2008)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2008 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"申請者は、活性化PDC形質細胞様樹状細胞特異的膜分子であるPDC-TREMを発見し、PDC-TREMがToll様受容体による核酸成分認識後のIFN産生調節に重要な役割を担っていること、を明らかにした。PDC-TREMに対する特異的モノクローナル抗体を複数樹立することに成功し、抗体処理によるI型IFN産生の著しい産生抑制を見出した。一方、リガンドであるSemaphorinを作用させることにより、PDC-TREM依存的にI型IFNが産生されることも見出した。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19590502, 研究期間(年度):2007-2008","subitem_description_type":"Other"},{"subitem_description":"出典：「形質細胞様樹状細胞特異的膜分子PDC-TREMのI型IFN産生増幅機構の解明」研究成果報告書　課題番号19590502\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19590502/19590502seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00056704","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学医薬保健研究域医学系 / 理化学研究所"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=70415339"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=70415339","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19590502/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19590502/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19590502/19590502seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19590502/19590502seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-27"}],"displaytype":"detail","filename":"ME-PR-WATARI-H-kaken 2009-4p.pdf","filesize":[{"value":"226.2 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-WATARI-H-kaken 2009-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/50395/files/ME-PR-WATARI-H-kaken 2009-4p.pdf"},"version_id":"68eb1b70-e7da-4e6c-a3b5-0debebd598ed"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"形質細胞様樹状細胞特異的膜分子PDC-TREMのI型IFN産生増幅機構の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"形質細胞様樹状細胞特異的膜分子PDC-TREMのI型IFN産生増幅機構の解明"},{"subitem_title":"Mechanisms in the augmentation of type I interferon production by PDC-TREM, a novel plasmacytoid dendritic cell specific receptor","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2825"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-01-27"},"publish_date":"2020-01-27","publish_status":"0","recid":"50395","relation_version_is_last":true,"title":["形質細胞様樹状細胞特異的膜分子PDC-TREMのI型IFN産生増幅機構の解明"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T14:13:22.296080+00:00"}