{"created":"2023-07-27T06:54:51.522017+00:00","id":50408,"links":{},"metadata":{"_buckets":{"deposit":"738b71f0-a63a-416a-89c9-2d485b06b429"},"_deposit":{"created_by":18,"id":"50408","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"50408"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00050408","sets":["2812:2813:2816"]},"author_link":["91235","91236"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-05-31","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2016-04-01 - 2018-03-31","bibliographic_titles":[{"bibliographic_title":"平成29(2017)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2017 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ino, Daisuke"}],"nameIdentifiers":[{"nameIdentifier":"91236","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40721981","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=40721981"}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ミトコンドリアは、エネルギー産生に重要な役割を果たす細胞内器官であるが、核内のゲノムDNAとは異なる独自のゲノム(ミトコンドリアDNA: mtDNA)を持つ。mtDNAの生理機能や病気への関連については未だ不明な点が多いが、その原因の一端として生きた細胞の中でmtDNAを解析するための手法が限られている点を挙げることができる。そこで、本研究では、mtDNAを生きた細胞の中で可視化・操作するための新規技術を開発することを目的とした。我々は、生きた細胞の中でDNAの構造を鮮明に可視化するための新規ツール ChrocodiLEの開発に成功した。","subitem_description_type":"Abstract"},{"subitem_description":"Mitochondria, organelles which play a central role in cellular energy production, have their own genome named mitochondrial DNA (mtDNA). The physiological and pathophysiological roles of mtDNA remain elusive partly because the techniques to analyze mtDNA function in living cells are still limited. In this research, we aimed to develop a new probe that allows us to visualize mtDNA dynamics and to artificially manipulate mtDNA state in living cells. We succeeded in generating a new fluorescent probe named ChrocodiLE, which enables us to visualize fine DNA structure in living cells.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:16K21634, 研究期間(年度):2016-04-01 - 2018-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「ミトコンドリアDNAを可視化・操作する新規ツール開発と生理機能解析」課題番号16K21634\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-16K21634/16K21634seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系 / 理化学研究所","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00056717","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=40721981"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=40721981","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K21634/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K21634/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-16K21634/16K21634seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-16K21634/16K21634seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"稲生, 大輔"}],"nameIdentifiers":[{"nameIdentifier":"91235","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40721981","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=40721981"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-01-27"}],"displaytype":"detail","filename":"ME-PR-INO-D-kaken 2018-4p.pdf","filesize":[{"value":"252.1 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-INO-D-kaken 2018-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/50408/files/ME-PR-INO-D-kaken 2018-4p.pdf"},"version_id":"bcbfd84f-1ff5-43bf-9fa1-070d3a329bc2"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ミトコンドリアDNAを可視化・操作する新規ツール開発と生理機能解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ミトコンドリアDNAを可視化・操作する新規ツール開発と生理機能解析"},{"subitem_title":"Development of a new probe for visualization and manipulation of mtDNA","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2816"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-01-27"},"publish_date":"2020-01-27","publish_status":"0","recid":"50408","relation_version_is_last":true,"title":["ミトコンドリアDNAを可視化・操作する新規ツール開発と生理機能解析"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-07-01T05:35:46.132366+00:00"}