{"created":"2023-07-27T06:54:53.057208+00:00","id":50446,"links":{},"metadata":{"_buckets":{"deposit":"d7c399c4-5ace-465a-8bbf-c9afe12f8fe9"},"_deposit":{"created_by":18,"id":"50446","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"50446"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00050446","sets":["2812:2813:2828"]},"author_link":["1871","91292"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-04","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"21p.","bibliographicVolumeNumber":"2004-2005","bibliographic_titles":[{"bibliographic_title":"平成17(2005)年度 科学研究費補助金 基盤研究(B) 研究成果報告書"},{"bibliographic_title":"2005 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"基礎研究\n平成16年の動物実験にて胸部交感神経(Th1-Th5)を切除した交感神経ブロックモデルにおいて,冠血流増加作用と心筋虚血耐性作用を確認した.\n臨床研究\n(1)高位硬膜外麻酔(TEA群)と全身麻酔(GA群)による冠動脈バイパス術における術中,術後の自律神経解析では,LF(交感神経の指標)はTEA群で有意に抑制され,HF(副交感神経の指標)はTEA群がGA群に比べ有意に活動性が高い事が解った.また不整脈の発生はTEA群で有意に少なく,TEAは交感神経を抑制し,不整脈の発生を減少させることが確認し論文報告した.\n(2)TEAによる頭蓋内の血流,酸素飽和度測定を行い.TEA群ではGA群に比べ血圧低下に伴うカテコールアミン投与量が少量であり,その結果血圧60以下となるようなAuto regulationから逸脱する症例が軽減され,結果として術中脳血流が安定することが判明した.\n(3)高位硬膜外麻酔によるAwake OPCABの臨床例60例を経験し,全身麻酔のみの冠動脈バイパス術に比べ術後回復が有意に早く,入院期間も短いことを報告した.\n(4)Awake OPCAB20例と全身麻酔のみの冠動脈バイパス術症例20例ずつにおいて,Mini-mental State Examination(MMSE) TestとBenton Visual Retention Testを術前,術後3日目,術後7日目に施行した.全身麻酔群で術後3日目において両テストともに有意に低い値を示し,局所麻酔によるAwake OPCABは全身麻酔によるCABGに比べ高次脳機能が維持されることが確認された.","subitem_description_type":"Abstract"},{"subitem_description":"Basic research\nIn 2004,we evaluated the effects of thoracic epidural anesthesia (TEA) to the coronary blood flow and the augmentation of tolerance for myocardial ischemia in acute myocardial models with rats.\nResults of this study presented that TEA increased the coronary blood flow and decreased the area of myocardial infarction after the coronary artery occlusion.\nClinical research\n1)We reported thoracic epidural anesthesia (TEA) inhibited the activation of sympathetic nerve strongly compared to general anesthesia and furthermore TEA reduced arrhythmia during CABG.\n2)We monitored the brain blood flows and the O2 saturation during off-pump CABG(OPCAB). The TEA stabilized the brain blood flow more than general anesthesia by avoiding the low blood pressure during the anastomosis.\n3)We reported 60 awake off pump CABG (AOCAB) by using TEA. The patients with AOCAB recovered faster than them of OPCAB with general anesthesia.\n4)We studied Mini-mental State Examination (MMSE) and Benton Visual Retention Test to the 20 patients with AOCAB and 20 with standard general anesthesia OPCAB. This study resulted AOCAB maintained higher level function of brain.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:16390392, 研究期間(年度):2004-2005","subitem_description_type":"Other"},{"subitem_description":"出典：「覚醒下冠動脈バイパス術に関する基礎的ならびに臨床的研究」研究成果報告書　課題番号16390392\n  (KAKEN：科学研究費助成事業データベース（国立情報学研究所）)\n　　　本文データは著者版報告書より作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00056755","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学医薬保健研究域医学系"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=60242492"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=60242492","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16390392/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16390392/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-16390392/163903922005kenkyu_seika_hokoku_gaiyo/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-16390392/163903922005kenkyu_seika_hokoku_gaiyo/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-02-03"}],"displaytype":"detail","filename":"ME-PR-WATANABE-G-kaken 2006-21p.pdf","filesize":[{"value":"1.5 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-WATANABE-G-kaken 2006-21p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/50446/files/ME-PR-WATANABE-G-kaken 2006-21p.pdf"},"version_id":"df5d03e1-cae9-4635-af72-f6f8158c2023"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"覚醒下冠動脈バイパス術に関する基礎的ならびに臨床的研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"覚醒下冠動脈バイパス術に関する基礎的ならびに臨床的研究"},{"subitem_title":"Basic and clinical research of awake off pump CABG","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2828"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-02-03"},"publish_date":"2020-02-03","publish_status":"0","recid":"50446","relation_version_is_last":true,"title":["覚醒下冠動脈バイパス術に関する基礎的ならびに臨床的研究"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T14:31:03.747473+00:00"}