{"created":"2023-07-27T06:54:53.327861+00:00","id":50453,"links":{},"metadata":{"_buckets":{"deposit":"1e7972d2-a700-4dc4-9164-6e52b5bf8bcb"},"_deposit":{"created_by":18,"id":"50453","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"50453"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00050453","sets":["2812:2813:2816"]},"author_link":["91308","139"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-06-29","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2014-04-01 - 2018-03-31","bibliographic_titles":[{"bibliographic_title":"平成29(2017)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2017 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"半減期7.2時間のα放射体211Atは核医学において、がん治療への応用が期待されるアイソトープの一つであるが、その利用は製造拠点に限られてきた。本研究では遠隔地での211Atを用いた研究を支援するための211Rn/211Atジェネレータを作成し、さらに炭素鎖数の多いアルカン類を用いた溶媒抽出系を採用することで、溶媒温度によるジェネレータの制御の可能性を検討した。検討の結果、炭素数の多いアルカンを冷却し固体化することにより211Rnを溶媒中に保持できることが示された。","subitem_description_type":"Abstract"},{"subitem_description":"Although an alpha emitter astatine-211 is the most promising radionuclide for treatment of cancer, its short half-life limited the use of it only at nearby hospitals. Here we produced 211Rn/211At generator using solvent extraction method, which enables to deliver 211At more distant site from production facilities. Moreover, we evaluated the retention of 211Rn in an organic solvent, or hydrocarbon by changing the temperature to change the phase of each hydrocarbon solvent.\n211Rn was produced by 209Bi(7Li, 5n)211Rn reaction at the JAEA-Tokai tandem accelerator. 211Rn was extracted by solvent extraction using decane, dodecane, tetradecane, hexadecane as organic solvents. These hydrocarbons were kept at a constant temperature (0 and 20 degrees), and the amount of 211 Rn was periodically measured. As a result, 211Rn was released from all the hydrocarbons at 20 degree, but in the case of hexadecane at 0 degree, 80 to 90% of 211Rn was retained for 10 hours.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:26461848, 研究期間(年度):2014-04-01 - 2018-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「物質の三態を制御したRn/Atジェネレータの開発とα線内用療法への展開」課題番号26461848\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-26461848/26461848seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"福島県立医科大学 / 金沢大学医薬保健研究域保健学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00056762","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=80313675"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=80313675","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26461848/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26461848/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-26461848/26461848seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-26461848/26461848seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-02-03"}],"displaytype":"detail","filename":"ME-PR-WASHIYAMA-K-kaken 2018-6p.pdf","filesize":[{"value":"230.3 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-WASHIYAMA-K-kaken 2018-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/50453/files/ME-PR-WASHIYAMA-K-kaken 2018-6p.pdf"},"version_id":"a604f8b0-8656-4247-b03a-f4338d062cfb"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"物質の三態を制御したRn/Atジェネレータの開発とα線内用療法への展開","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"物質の三態を制御したRn/Atジェネレータの開発とα線内用療法への展開"},{"subitem_title":"Development of a matter phase controlled Rn/At generator for targeted alpha therapy","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2816"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-02-03"},"publish_date":"2020-02-03","publish_status":"0","recid":"50453","relation_version_is_last":true,"title":["物質の三態を制御したRn/Atジェネレータの開発とα線内用療法への展開"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T12:51:01.639553+00:00"}