{"created":"2023-07-27T06:54:56.520082+00:00","id":50530,"links":{},"metadata":{"_buckets":{"deposit":"6b8c27ff-a594-45a3-ae4f-9dd79707441c"},"_deposit":{"created_by":18,"id":"50530","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"50530"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00050530","sets":["2812:2813:2825"]},"author_link":["91488","20737"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2007-2008","bibliographic_titles":[{"bibliographic_title":"平成20(2008)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2008 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"癌の診断、治療を目的とした放射性薬剤の開発を目的として、シグマレセプターをターゲットとした新規薬剤の開発を試みた。放射性ヨウ素標識ベサミコール誘導体([^(125)I]pIV)を作製し、担癌マウスを用いて[^(125)I]pIVの体内放射能分布を評価した結果、腫瘍へ高い放射能集積を示した。次に、治療用核種である^(131)Iを用い[^(131)I]pIVを作製し、治療実験を行った結果、[^(131)I]pIV投与群は、非投与群に比べ、腫瘍の増殖を抑制する傾向が観察され、本薬剤が有効である可能性が示された。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19591404, 研究期間(年度):2007-2008","subitem_description_type":"Other"},{"subitem_description":"出典：「シグマレセプター標的包括的癌治療法の確立を目指した新規放射性薬剤の開発と評価」研究成果報告書　課題番号19591404\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19591404/19591404seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00056839","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学学際科学実験センター"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=90019604"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=90019604","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19591404/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19591404/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19591404/19591404seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19591404/19591404seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-02-07"}],"displaytype":"detail","filename":"AD-PR-MORI-H-kaken 2009-4p.pdf","filesize":[{"value":"61.6 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"AD-PR-MORI-H-kaken 2009-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/50530/files/AD-PR-MORI-H-kaken 2009-4p.pdf"},"version_id":"2a6559fb-d303-4d45-9a0d-d2b574e87f57"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"シグマレセプター標的包括的癌治療法の確立を目指した新規放射性薬剤の開発と評価","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"シグマレセプター標的包括的癌治療法の確立を目指した新規放射性薬剤の開発と評価"},{"subitem_title":"Development and evaluation of novel radiopharmaceuticals which are targeted to sigma receptors for comprehensive cancer therapy","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2825"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-02-07"},"publish_date":"2020-02-07","publish_status":"0","recid":"50530","relation_version_is_last":true,"title":["シグマレセプター標的包括的癌治療法の確立を目指した新規放射性薬剤の開発と評価"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T14:13:31.173708+00:00"}