{"created":"2023-07-27T06:55:24.815450+00:00","id":51249,"links":{},"metadata":{"_buckets":{"deposit":"dec6e101-1021-43f5-b851-1644242c2b81"},"_deposit":{"created_by":18,"id":"51249","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"51249"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00051249","sets":["2812:2813:4085"]},"author_link":["87685","87686"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-05-27","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"8p.","bibliographicVolumeNumber":"2019-04-01 – 2022-03-31","bibliographic_titles":[{"bibliographic_title":"令和3(2021)年度 科学研究費補助金 基盤研究(B) 研究成果報告書"},{"bibliographic_title":"2021 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Immune system plays an important role in host defense against pathogens and tumor cells. However, it is known that pathogens and tumor cells have acquired various immune evasion mechanisms to escape from the host immune system. This study revealed that certain immune inhibitory receptors recognize specific bacteria and that both immune inhibitory receptors and their bacterial ligands show genetic diversity. These results suggest that host and bacteria have coevolved through immune inhibitory receptor-mediated bacterial immune evasion mechanisms.","subitem_description_type":"Abstract"},{"subitem_description":"免疫は、病原体や腫瘍細胞を排除するための生体防御システムである。しかしながら、病原体や腫瘍細胞は、免疫から逃れるために様々な免疫逃避機構を発達させていることがわかってきた。本研究により、新たに免疫抑制化レセプターが特定の細菌を認識すること、このような免疫抑制化レセプターと細菌リガンドが遺伝的多様性を示すことが明らかとなり、免疫抑制化レセプターを介した細菌の免疫逃避機構によって宿主と細菌が共進化している可能性が考えられた。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19H03468, 研究期間(年度):2019-04-01 – 2022-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「免疫逃避機構に着目した宿主細菌相互作用の解明」課題番号19H03468\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19H03468/19H03468seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学先進予防医学研究センター","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00057552","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=30585170"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=30585170","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19H03468/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19H03468/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19H03468/19H03468seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19H03468/19H03468seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-02-03"}],"displaytype":"detail","filename":"ME-PR-HIRAYASU-K-kaken 2022-8p.pdf","filesize":[{"value":"289.8 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-HIRAYASU-K-kaken 2022-8p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/51249/files/ME-PR-HIRAYASU-K-kaken 2022-8p.pdf"},"version_id":"f7c4b8e1-3e99-422f-850a-631a888d05dc"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"免疫逃避機構に着目した宿主細菌相互作用の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"免疫逃避機構に着目した宿主細菌相互作用の解明"},{"subitem_title":"Host-bacteria interactions through immune evasion mechanism","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["4085"],"pubdate":{"attribute_name":"公開日","attribute_value":"2023-02-03"},"publish_date":"2023-02-03","publish_status":"0","recid":"51249","relation_version_is_last":true,"title":["免疫逃避機構に着目した宿主細菌相互作用の解明"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T10:39:12.717234+00:00"}