@techreport{oai:kanazawa-u.repo.nii.ac.jp:00051594, month = {May}, note = {本研究はケニア小児の腸内寄生原虫の感染危険因子を調査した。HIV感染児のアメーバ感染率は非感染児より低かった(63.2% vs. 78.8%, P=0.02)、高いCD4/CD8比はアメーバ感染と関連していた(OR 3.3, P<0.01)。HIV感染女児のジアルジアBの感染率はHIV感染男児とHIV非感染女児より低かった(15.6% vs. 40.5% と37.8%、P<0.01と0.02)。また、飲用水の煮沸しないこと(OR 3.88, P=0.04)および兄弟などの世話をすること(OR 2.8, P=0.01)はジアルジアB感染の危険因子であった。, We investigated the prevalence and risk factors of Entamoeba species and Giardia intestinalis infections in Kenyan children with and without HIV infection. The rate of Entamoeba spp. infection in HIV-infected children [HIV(+)] was lower than in HIV-uninfected children [HIV(─)] (63.2% vs. 78.8%, P=0.02), and CD4/CD8 ratio was related with it (≧1 vs. <1, OR 3.3, P<0.01). For Giardia assemblage B infection, the rate in HIV(+) females was lower than in HIV(+) males and HIV(─) females (15.6% vs. 40.5% and 37.8%, P<0.01 and 0.02), no boiling drinking water (OR 3.8, P=0.04) and nursery care of siblings (OR 2.8, P=0.01) were risk factors. Entamoeba and Giardia assemblage B infections were incoherently correlated with HIV infection. Entamoeba infection maybe be an indicator of the children’s better immune status, whereas Giardia assemblage B infection was related to hygienic conditions. The hygienic quality of drinking water needs to be improved to prevent the Giardia infection., 研究課題/領域番号:16H05842, 研究期間(年度):2016-04-01 - 2020-03-31, 出典:「ケニアのHIV感染および非感染小児下痢症における腸管寄生原虫の役割」研究成果報告書 課題番号16H05842 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-16H05842/16H05842seika/)を加工して作成, 金沢大学医薬保健研究域医学系}, title = {ケニアのHIV感染および非感染小児下痢症における腸管寄生原虫の役割}, year = {2020} }