{"created":"2023-07-27T06:55:33.721258+00:00","id":51604,"links":{},"metadata":{"_buckets":{"deposit":"804ea1c2-5ec4-4967-9a30-9c1f0a07020a"},"_deposit":{"created_by":18,"id":"51604","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"51604"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00051604","sets":["2812:2813:3929"]},"author_link":["80067","355"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-05-26","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"15p.","bibliographicVolumeNumber":"2017-04-01 - 2020-03-31","bibliographic_titles":[{"bibliographic_title":"令和1(2019)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2019 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"イソシアニドジクロリドを活用した新規複素環化合物合成法の開発を行った\nまず，イソシアニドジクロリドを活用した，多官能性ジヒドロオキサゾール誘導体の高効率的合成法を開発した。すなわち，α位にトシル基を有するイソシアニド(TosMIC)から誘導したイソシアニドジクロリドとアルデヒドとのアルドール型反応により，簡便に2-クロロジヒドロオキサゾール誘導体が得られた。また，α,β-不飽和カルボニル化合物にとイソシアニドジクロリドとのマイケル付加-環化反応，続くトシル基のE2脱離，トシル基の付加－脱離反応，芳香族化によって多置換ピロール誘導体が得られることを見出した","subitem_description_type":"Abstract"},{"subitem_description":"Multifunctionalized oxazoles and pyrroles are important building blocks in organic synthesis as well as in pharmaceuticals, natural products, and functional materials. In this study, a novel synthetic method for multifunctional oxazole and pyrrole derivatives has been achieved. We focused on the utility of isocyanide dichloride, which is a stable and readily available chemical species via addition of chlorine onto isocyanides. The presence of the two halogen atoms activates the C=N double bond toward nucleophiles, which realizes nucleophilic additions in a sequential manner. We initially examined whether isocyanide dichloride which was easily prepared from the corresponding TosMIC with SO2Cl2, could synthesize oxazole and pyrrole derivatives.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:17K05778, 研究期間(年度):2017-04-01 - 2020-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：「イソシアニドと共役拡張型1,3-双極子による高効率的複素環合成手法の開発」研究成果報告書　課題番号17K05778\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-17K05778/17K05778seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学理工研究域物質化学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00057907","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=10506819"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=10506819","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K05778/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K05778/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-17K05778/17K05778seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-17K05778/17K05778seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-04-22"}],"displaytype":"detail","filename":"SC-PR-SOETA-T-kaken 2020-15p.pdf","filesize":[{"value":"185.5 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"SC-PR-SOETA-T-kaken 2020-15p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/51604/files/SC-PR-SOETA-T-kaken 2020-15p.pdf"},"version_id":"44052859-11f7-487d-86c2-4694e90f9e14"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"イソシアニドと共役拡張型1,3-双極子による高効率的複素環合成手法の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"イソシアニドと共役拡張型1,3-双極子による高効率的複素環合成手法の開発"},{"subitem_title":"Development of the efficient synthetic method for heterocycles utilized by isocyanide and conjugated 1,3-dipolar","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["3929"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-04-22"},"publish_date":"2021-04-22","publish_status":"0","recid":"51604","relation_version_is_last":true,"title":["イソシアニドと共役拡張型1,3-双極子による高効率的複素環合成手法の開発"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T14:05:09.236643+00:00"}