{"created":"2023-07-27T06:55:35.826553+00:00","id":51664,"links":{},"metadata":{"_buckets":{"deposit":"bb625f6b-4e78-4c1f-89e3-5c936fcff9a9"},"_deposit":{"created_by":18,"id":"51664","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"51664"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00051664","sets":["2812:2813:4014"]},"author_link":["26970","69579"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-06-27","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"9p.","bibliographicVolumeNumber":"2017-04-01 – 2021-03-31","bibliographic_titles":[{"bibliographic_title":"令和2(2020)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2020 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"宿主内におかれた細菌は，宿主内環境を感知して遺伝子発現を変化させ，宿主内の環境に適応して生存をつづけるとともに，宿主への毒性を変化させて傷害を与えたりする。大腸菌の二成分制御系の中には，宿主内で活性化して宿主殺傷能を増減する種類が存在した。このうち，EnvZとOmpRにより制御される遺伝子群の中に，宿主殺傷能を担う種類が存在した。この遺伝子は，未知の毒性因子の細菌内の量を変化させて，細菌の宿主への傷害性を調節すると考えられた。","subitem_description_type":"Abstract"},{"subitem_description":"Bacteria under hostile environmental conditions change their gene expression with aid of the two-component system (TCS), a bacterial signaling system, to adapt and survive in the host. This study identified several genes coding TCS factors acted for regulation of bacterial virulence. EnvZ-OmpR regulated one gene that codes membrane-located protein to enhance host-killing activity through altering level of unknown virulence factor in bacteria.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:17K07331, 研究期間(年度):2017-04-01 – 2021-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：「宿主内で活性化する細菌遺伝子発現制御系と食細胞を介する感染調節」研究成果報告書　課題番号17K07331\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-17K07331/17K07331seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"札幌医科大学 / 金沢大学医薬保健研究域薬学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00057967","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=90303297"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=90303297","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K07331/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K07331/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-17K07331/17K07331seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-17K07331/17K07331seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-02-28"}],"displaytype":"detail","filename":"PH-PR-SHIRATSUCHI-A-kaken 2021-9p.pdf","filesize":[{"value":"87.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"PH-PR-SHIRATSUCHI-A-kaken 2021-9p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/51664/files/PH-PR-SHIRATSUCHI-A-kaken 2021-9p.pdf"},"version_id":"2c94ce4a-319d-45d3-9da1-82fa5b2d4d36"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"宿主内で活性化する細菌遺伝子発現制御系と食細胞を介する感染調節","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"宿主内で活性化する細菌遺伝子発現制御系と食細胞を介する感染調節"},{"subitem_title":"Study on bacterial gene expression activated in host and regulation of phagocytosis-mediated infectious diseases","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["4014"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-02-28"},"publish_date":"2022-02-28","publish_status":"0","recid":"51664","relation_version_is_last":true,"title":["宿主内で活性化する細菌遺伝子発現制御系と食細胞を介する感染調節"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:45:04.997672+00:00"}