{"created":"2023-07-27T06:55:35.872422+00:00","id":51665,"links":{},"metadata":{"_buckets":{"deposit":"67aa31b8-53f4-4178-b787-fdfbbd17b489"},"_deposit":{"created_by":18,"id":"51665","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"51665"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00051665","sets":["2812:2813:4014"]},"author_link":["19995","382"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-05-18","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2018-04-01 - 2021-03-31","bibliographic_titles":[{"bibliographic_title":"令和2(2020)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2020 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"EOB造影MRIの動脈相画像の問題点としてtransient severe motion（TSM）と呼ばれる画像不良の出現がある。我々はTSMの発生には一過性の腹壁の運動が大きく関与していること、および、EOB投与によるTSM発生はEOBが中枢神経系に直接作用して生じる可能性が高いことを明らかにした。また、肝細胞相画像における問題点である肝予備能低下例での画質低下の早期予測を目的に、臨床例を用いて肝細胞へのEOB取り込みの経時的変化の詳細を明らかにした。","subitem_description_type":"Abstract"},{"subitem_description":"One of the disadvantages of EOB contrast-enhanced MRI in screening for hepatocellular carcinoma is poor arterial phase imaging, called transient severe motion (TSM). We have shown that transient severe motion of the abdominal wall plays a major role in the development of TSM. We also examined the appearance of TSMs in rats treated with EOB in animal experiments, and found that TSMs caused by EOB administration are most likely caused by the direct effect of EOB on the central nervous system. In order to predict the early deterioration of image quality in cases of reduced hepatic reserve, which is a problem in hepatocellular phase imaging, we clarified the details of temporal changes in EOB uptake into hepatocytes using clinical cases.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:18K07669, 研究期間(年度):2018-04-01 - 2021-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：「進行肝臓病患者に対するMRIを用いた早期肝細胞癌スクリーニング手技の確立」研究成果報告書　課題番号18K07669\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-18K07669/18K07669seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域保健学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00057968","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学医薬保健研究域保健学系"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=30313638"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=30313638","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K07669/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K07669/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-18K07669/18K07669seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-18K07669/18K07669seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-02-18"}],"displaytype":"detail","filename":"ME-PR-KOBAYASHI-S-kaken 2021-6p.pdf","filesize":[{"value":"157.9 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-KOBAYASHI-S-kaken 2021-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/51665/files/ME-PR-KOBAYASHI-S-kaken 2021-6p.pdf"},"version_id":"6d2dd323-f7ae-4c2c-a55d-0e6c9b790fbd"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"進行肝臓病患者に対するMRIを用いた早期肝細胞癌スクリーニング手技の確立","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"進行肝臓病患者に対するMRIを用いた早期肝細胞癌スクリーニング手技の確立"},{"subitem_title":"Establishment of an MRI-based screening technique for early-stage hepatocellular carcinoma in patients with advanced liver disease","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["4014"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-02-18"},"publish_date":"2022-02-18","publish_status":"0","recid":"51665","relation_version_is_last":true,"title":["進行肝臓病患者に対するMRIを用いた早期肝細胞癌スクリーニング手技の確立"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:50:13.086868+00:00"}