{"created":"2023-07-27T06:55:38.568890+00:00","id":51735,"links":{},"metadata":{"_buckets":{"deposit":"2cbba692-e2ea-42c2-a4bd-a2e378eab410"},"_deposit":{"created_by":18,"id":"51735","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"51735"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00051735","sets":["2812:2813:4014"]},"author_link":["10719","86156"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-06-15","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"10p.","bibliographicVolumeNumber":"2017-04-01 - 2021-03-31","bibliographic_titles":[{"bibliographic_title":"令和2(2020)年度 科学研究費補助金 基盤研究(B) 研究成果報告書"},{"bibliographic_title":"2020 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Satoh, Makoto"}],"nameIdentifiers":[{"nameIdentifier":"10719","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"30345235","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=30345235"}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Since various regions of the brain are composed of functional units called columnar structures, understanding the molecular mechanisms of column formation is an important research topic in neuroscience. However, the mechanism by which column structures are formed from different cell populations during development is still largely unknown. Using the Drosophila visual center, which has a simple column structure, as a model system, we have elucidated the evolutionarily conserved mechanism of column formation. Specifically, we elucidated the mechanism of column formation by differential cell adhesion between core columnar neurons and repulsive effects between neurons of the same lineage. We also elucidated the molecular mechanism that determines the orientation of the neurons constituting the column.","subitem_description_type":"Abstract"},{"subitem_description":"脳の様々な領域はカラム構造と呼ばれる機能単位から成るため、カラムが形成される分子機構を理解することは神経科学において重要な研究課題である。しかし発生過程においてどのような細胞集団からどのようにカラム構造が作り出されるのか、そのメカニズムついてはほとんど分かっていなかった。シンプルなカラム構造を持つショウジョウバエ視覚中枢をモデル系として、進化的に保存されたカラム形成機構を明らかにした。具体的には、カラムを構成する神経細胞間の細胞接着力の差分、および細胞系譜に応じた神経細胞間の反発作用によるカラム形成機構を解明した。また、カラムを構成する神経細胞の方向性を決定する分子機構を解明した。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:17H03542, 研究期間(年度):2017-04-01 - 2021-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「機能的な脳カラム構造形成を制御する分子機構」課題番号17H03542\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-17H03542/17H03542seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学新学術創成研究機構","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00058038","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=30345235"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=30345235","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17H03542/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17H03542/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-17H03542/17H03542seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-17H03542/17H03542seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐藤, 純"}],"nameIdentifiers":[{"nameIdentifier":"86156","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"30345235","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=30345235"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-03-02"}],"displaytype":"detail","filename":"FR-PR-SATO-M-kaken 2022-10p.pdf","filesize":[{"value":"93.3 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"FR-PR-SATO-M-kaken 2022-10p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/51735/files/FR-PR-SATO-M-kaken 2022-10p.pdf"},"version_id":"9d1c4a1b-2bb6-43d3-bd94-94087dd940c1"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"機能的な脳カラム構造形成を制御する分子機構","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"機能的な脳カラム構造形成を制御する分子機構"},{"subitem_title":"Molecular mechanisms that regulate the formation of functional columnar unit in the brain","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["4014"],"pubdate":{"attribute_name":"公開日","attribute_value":"2023-03-02"},"publish_date":"2023-03-02","publish_status":"0","recid":"51735","relation_version_is_last":true,"title":["機能的な脳カラム構造形成を制御する分子機構"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-07-01T05:19:35.736556+00:00"}