{"created":"2023-07-27T06:55:39.020749+00:00","id":51760,"links":{},"metadata":{"_buckets":{"deposit":"4740d899-9a8f-456c-8542-7c1873924cdb"},"_deposit":{"created_by":18,"id":"51760","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"51760"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00051760","sets":["2812:2813:4085"]},"author_link":["78915","405"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-06-09","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2019-04-01 - 2022-03-31","bibliographic_titles":[{"bibliographic_title":"令和3(2021)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2021 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We performed basic experiments to develop a treatment combining IVR and nanoparticles to synergistically amplify anticancer activity while reducing side effects and showed that fibrin glue could be used as a carrier to directly and efficiently deliver nanoparticles to target tissues using IVR techniques. We also showed that cooling the fibrin glue controlled the rate of gelation and provided a delayed reaction effect suitable for clinical use.","subitem_description_type":"Abstract"},{"subitem_description":"IVRとナノ粒子を組み合わせることにより、副作用を軽減しながら相乗的に抗癌作用を増幅させる治療の開発するための基礎的実験を行った。IVR手技を用いてナノ粒子を直接的に効率よく目的組織に送達するための担体としてフィブリン糊が使用できることを確認した。また、フィブリン糊を冷却してゲル化の速度をコントロールすることにより、臨床使用に適した反応遅延効果を得られることを確認した。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19K08118, 研究期間(年度):2019-04-01 - 2022-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「IVRとナノメディシンの併用によるがんターゲティングおよび微小環境の制御」課題番号19K08118\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19K08118/19K08118seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00058063","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=30401920"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=30401920","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K08118/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K08118/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19K08118/19K08118seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19K08118/19K08118seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-02-06"}],"displaytype":"detail","filename":"ME-PR-KODA-W-kaken 2022-6p.pdf","filesize":[{"value":"639.6 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-KODA-W-kaken 2022-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/51760/files/ME-PR-KODA-W-kaken 2022-6p.pdf"},"version_id":"d3bee8f3-f587-4b09-91b7-7df3315493d7"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"IVRとナノメディシンの併用によるがんターゲティングおよび微小環境の制御","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"IVRとナノメディシンの併用によるがんターゲティングおよび微小環境の制御"},{"subitem_title":"Cancer Targeting and Microenvironment Control by Combination of IVR and Nanomedicine","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["4085"],"pubdate":{"attribute_name":"公開日","attribute_value":"2023-02-06"},"publish_date":"2023-02-06","publish_status":"0","recid":"51760","relation_version_is_last":true,"title":["IVRとナノメディシンの併用によるがんターゲティングおよび微小環境の制御"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T10:37:36.808653+00:00"}