{"created":"2023-07-27T06:55:39.161327+00:00","id":51764,"links":{},"metadata":{"_buckets":{"deposit":"12bb1b5c-3ba0-4736-a713-30631ce308a7"},"_deposit":{"created_by":18,"id":"51764","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"51764"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00051764","sets":["2812:2813:4014"]},"author_link":["21870","93232"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-04-27","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2019-04-01 - 2021-03-31","bibliographic_titles":[{"bibliographic_title":"令和2(2020)年度 科学研究費補助金 若手研究 研究成果報告書"},{"bibliographic_title":"2020 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本研究において我々は，脂肪肝炎関連肝癌患者の末梢血および肝細胞癌組織浸潤免疫細胞の解析を行い，肝線維化進行や肝癌発症に関わる免疫担当細胞の特徴を明らかにした．脂肪肝炎関連肝癌はウイルス関連肝癌と比較して，樹状細胞をはじめとする免疫細胞プロファイルにおいて大きな違いが認められ，その結果は治療効果や予後と関連する傾向にあった．","subitem_description_type":"Abstract"},{"subitem_description":"In this study, we analyzed the peripheral blood and hepatocellular carcinoma tissue-infiltrating immune cells of patients with steatohepatitis-related hepatocellular carcinoma to characterize the immune cells involved in liver fibrosis progression and hepatocarcinogenesis. Compared with virus-related hepatocellular carcinoma, steatohepatitis-related hepatocellular carcinoma showed significant differences in immune cell profiles, including dendritic cells, which tended to be associated with treatment response and prognosis.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19K17455, 研究期間(年度):2019-04-01 - 2021-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：「単一細胞解析を用いた脂肪肝炎関連肝癌における抗腫瘍免疫の解明」研究成果報告書　課題番号19K17455\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19K17455/19K17455seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院研修医・専門医総合教育センター","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00058067","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=70632660"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=70632660","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K17455/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K17455/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19K17455/19K17455seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19K17455/19K17455seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-02-18"}],"displaytype":"detail","filename":"HO-PR-KITAHARA-M-kaken 2021-5p.pdf","filesize":[{"value":"78.0 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-KITAHARA-M-kaken 2021-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/51764/files/HO-PR-KITAHARA-M-kaken 2021-5p.pdf"},"version_id":"70d40537-7d6d-49fc-9eee-c3a1f6a70cd4"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"単一細胞解析を用いた脂肪肝炎関連肝癌における抗腫瘍免疫の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"単一細胞解析を用いた脂肪肝炎関連肝癌における抗腫瘍免疫の解明"},{"subitem_title":"Analysis of anti-tumor immunity in steatohepatitis-related hepatocellular carcinoma","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["4014"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-02-18"},"publish_date":"2022-02-18","publish_status":"0","recid":"51764","relation_version_is_last":true,"title":["単一細胞解析を用いた脂肪肝炎関連肝癌における抗腫瘍免疫の解明"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:49:55.008281+00:00"}