{"created":"2023-07-27T06:55:53.709021+00:00","id":52359,"links":{},"metadata":{"_buckets":{"deposit":"cef378b7-3739-4d36-b0ed-be813fd12a58"},"_deposit":{"created_by":18,"id":"52359","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"52359"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00052359","sets":["2812:2813:4014"]},"author_link":["109"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-06-01","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2018-04-01 – 2021-03-31","bibliographic_titles":[{"bibliographic_title":"令和2(2020)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2020 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{},{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"胚移植のためのレシピエントマウスにはICR系統を用いるが，小規模自家生産できず，肥満により使用期間が限られる。これらの欠点を補うため，多産で哺育能力に優れた近交系由来のレシピエントマウスを開発した。アルビノ近交系のKSマウスは，胚移植後帝王切開を要する事がほとんどなく，作業の省力化と使用動物数の削減が可能であった。遺伝子改変マウスの作出で多用されるC57BL/6系統の凍結融解受精卵を卵管内移植した時の離乳率は，採卵後凍結せずに直接移植した場合の成績と比べても低下しておらず，胚移植用レシピエントマウスとしての優位性を示した。","subitem_description_type":"Abstract"},{"subitem_description":"As a recipient mouse for embryo transfer, it is common to use the ICR strain. The ICR strain cannot be produced in-house on a small scale, and its period of use is limited due to obesity. We have developed inbred-derived recipient mice to replace the closed colony ICR strain. Albino inbred KS mice rarely required cesarean section after embryo transfer, which made it possible to save labor and reduce the number of animals used. The weaning rate when frozen and thawed fertilized eggs of the C57BL/6 strain, which are often used in the production of genetically modified mice, was transplanted intraoductally did not decrease compared to the results when directly transplanted without freezing after egg collection. These show the excellent properties of KS mice as embryo transfer recipient mice.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:18K06026, 研究期間(年度):2018-04-01 – 2021-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：「胚移植レシピエントのための新規アルビノ近交系マウスの開発」研究成果報告書　課題番号18K06026\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-18K06026/18K06026seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学学際科学実験センター","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00058653","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=50242524"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=50242524","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-18K06026/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-18K06026/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-18K06026/18K06026seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-18K06026/18K06026seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-02-21"}],"displaytype":"detail","filename":"AC-PR-HASHIMOTO-N-kaken 2021-5p.pdf","filesize":[{"value":"208.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"AC-PR-HASHIMOTO-N-kaken 2021-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/52359/files/AC-PR-HASHIMOTO-N-kaken 2021-5p.pdf"},"version_id":"5c265cee-d092-4207-8e11-787cc25b6576"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"胚移植レシピエントのための新規アルビノ近交系マウスの開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"胚移植レシピエントのための新規アルビノ近交系マウスの開発"},{"subitem_title":"Development of new albino inbred strain mice for embryo-transfer recipient","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["4014"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-02-21"},"publish_date":"2022-02-21","publish_status":"0","recid":"52359","relation_version_is_last":true,"title":["胚移植レシピエントのための新規アルビノ近交系マウスの開発"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:49:05.349221+00:00"}