{"created":"2023-07-27T06:56:02.237180+00:00","id":52595,"links":{},"metadata":{"_buckets":{"deposit":"59ffd89b-3f40-4387-9661-7021e4145009"},"_deposit":{"created_by":18,"id":"52595","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"52595"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00052595","sets":["2812:2813:2817"]},"author_link":["2647"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-05-09","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2015-04-01 – 2017-03-31","bibliographic_titles":[{"bibliographic_title":"平成28(2016)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2016 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本研究課題の目的は、腸内細菌叢と腎臓病の関連を解明し、その成果から腎臓病に対する新たなバイオマーカー候補を同定することである。近年、細菌叢と様々な疾患の関連が注目されている。腎臓病と細菌叢の関連についてもその解明が望まれている。\n急性腎障害モデルマウスを作成し、細菌叢の変化を16S rRNA解析により解析し、腎臓害で変化する細菌群を同定した。上記研究成果は、新たな急性腎障害における腸内環境が変化することを示唆している指標として現在、菌の同定とその意義の詳細な検討をすすめている。","subitem_description_type":"Abstract"},{"subitem_description":"The aim of this study was to reveal the relationship between gut microbiota and kidney disease and to identify new biomarkers for kidney diseases. The contribution of gut microbiota to various disorders has been reported in recent years. However, the association of gut microbiota with kidney disease remains to be investigated. We revealed the alteration of gut bacteria in acute kidney injury mice with 16S rRNA analysis. This result raise the possibility that gut bacteria could be a new candidate of biomarkers for acute kidney injury. A patent has been applied for the biomarker of kidney injury according to our results.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:15K19450, 研究期間(年度):2015-04-01 – 2017-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：「腸管免疫を介した腎・腸連関機序の解明」研究成果報告書　課題番号15K19450\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-15K19450/15K19450seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00058889","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=10749360"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=10749360","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-15K19450/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-15K19450/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-15K19450/15K19450seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-15K19450/15K19450seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-07-20"}],"displaytype":"detail","filename":"HO-PR-NAKADE-Y-kaken 2017-4p.pdf","filesize":[{"value":"229.6 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-NAKADE-Y-kaken 2017-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/52595/files/HO-PR-NAKADE-Y-kaken 2017-4p.pdf"},"version_id":"e379ac2d-4451-4a75-bb81-1c49d9f6423d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"腸管免疫を介した腎・腸連関機序の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"腸管免疫を介した腎・腸連関機序の解明"},{"subitem_title":"Impact of a specific gut microbiota change on acute kidney injury mice","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2817"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-07-20"},"publish_date":"2020-07-20","publish_status":"0","recid":"52595","relation_version_is_last":true,"title":["腸管免疫を介した腎・腸連関機序の解明"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T11:19:55.496560+00:00"}