{"created":"2023-07-27T06:56:03.567964+00:00","id":52624,"links":{},"metadata":{"_buckets":{"deposit":"e884ba8a-cf12-4c02-a53b-fffe1d11da12"},"_deposit":{"created_by":18,"id":"52624","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"52624"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00052624","sets":["2812:2813:3929"]},"author_link":["29851","23539"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-04-27","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"8p.","bibliographicVolumeNumber":"2017-04-01 – 2020-03-31","bibliographic_titles":[{"bibliographic_title":"令和1(2019)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2019 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本申請研究では、以下の3つのことを組織学的に検討することを目的とした。①薬物を使用した膝蓋大腿関節症モデルラットの確立、②変形性関節症（OA）の進行に荷重が及ぼす影響、③関節構成体に非荷重環境が及ぼす影響\nその結果、①従来脛骨大腿関節においてOAを惹起するために用いられている薬物を使用することで膝蓋大腿関節に対してもOAに典型的な組織学的変化を引き起こすこと、②非荷重環境によってOA進行が抑制されること、③非荷重環境は関節軟骨に対して廃用性の組織学的変化を引き起こすが、滑膜および膝蓋下脂肪体に対しては明らかな組織学的変化を引き起こさないことが明らかになった。","subitem_description_type":"Abstract"},{"subitem_description":"The purpose of this study was to examine the following three things histologically.; ①Establishment of osteoarthritis (OA) rat model in patellofemoral joint induced by MIA, ②Effect of joint loading on the progression of OA, ③Effect of unloading environment on joint compoenents.\nAs a result, this study revealed the following findings.; ① Intra-articular injection of MIA induced the typical histological changes in the patellofemoral joint, ② Joint unloading inhibits articular cartilage degeneration in knee joint, ③ Unloading environment caused disuse histological changes in the articular cartilage, however, it caused no critical histological changes to the synovial membrane or infrapatellar fat pad.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:17K13051, 研究期間(年度):2017-04-01 – 2020-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：「膝蓋大腿関節症モデルラットの確立と力学的負荷がもたらす病理組織学的変化」研究成果報告書　課題番号17K13051\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-17K13051/17K13051seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00058918","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=30743835"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=30743835","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-17K13051/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-17K13051/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-17K13051/17K13051seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-17K13051/17K13051seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-05-13"}],"displaytype":"detail","filename":"HO-PR-TAKAHASHI-I-kaken 2020-8p.pdf","filesize":[{"value":"131.9 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-TAKAHASHI-I-kaken 2020-8p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/52624/files/HO-PR-TAKAHASHI-I-kaken 2020-8p.pdf"},"version_id":"9868964e-c759-4c37-89e0-221d0dea6048"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"膝蓋大腿関節症モデルラットの確立と力学的負荷がもたらす病理組織学的変化","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"膝蓋大腿関節症モデルラットの確立と力学的負荷がもたらす病理組織学的変化"},{"subitem_title":"Establishment of rat model in patellofemoral osteoarthritis and histopathological changes induced by mechanical load","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["3929"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-05-13"},"publish_date":"2021-05-13","publish_status":"0","recid":"52624","relation_version_is_last":true,"title":["膝蓋大腿関節症モデルラットの確立と力学的負荷がもたらす病理組織学的変化"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T14:09:53.607938+00:00"}