{"created":"2023-07-27T06:56:04.385175+00:00","id":52658,"links":{},"metadata":{"_buckets":{"deposit":"1f10fa0f-4421-4877-8a85-d54ff13f456b"},"_deposit":{"created_by":18,"id":"52658","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"52658"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00052658","sets":["2812:2813:4085"]},"author_link":["94113"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-06-13","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2020-04-01 – 2022-03-31","bibliographic_titles":[{"bibliographic_title":"令和3(2021)年度 科学研究費補助金 若手研究 研究成果報告書"},{"bibliographic_title":"2021 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ueoka, Ken"}],"nameIdentifiers":[{"nameIdentifier":"94113","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60823010","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=60823010"}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Adipose tissue-derived somatic stem cell (ADSC) culture and sheet preparation were possible. The use of white rabbits to create a necrotic femoral head model was also possible, but the extent of necrosis varied, and there was no statistically significant difference in the degree of necrosis regeneration between the groups using ADSCs and ADSC sheets. The variability of the necrosis area in the necrosis modeling process may also have contributed to the variability of the results. We investigated the regeneration process of cartilage defects in a white rabbit osteoarthritis model, which we thought would reduce the variability of the model, and obtained results suggesting that the ADSC sheet may contribute to cartilage regeneration.","subitem_description_type":"Abstract"},{"subitem_description":"脂肪組織由来体性幹細胞（ADSC）の培養、シート作成に関しては、再現性の高いものとなった。白色家兎を使用した大腿骨頭壊死モデルの作成も可能であったが、壊死範囲にはばらつきが生じていた。ADSCとADSCシートを用いた群間では、壊死の再生程度において統計学的に有意といえる差までは認めなかった。壊死モデル作成において、壊死領域にもばらつきが生じやすく、その点も結果のばらつきにつながったと考えられた。モデルのばらつきが小さくなると考えて、白色家兎を用いた変形性関節症モデルを作成し、軟骨欠損の再生過程について調査した。ADSCシートが軟骨再生に寄与するのではないかと示唆される結果を得た。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:20K17992, 研究期間(年度):2020-04-01 – 2022-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「独自開発したシート状脂肪幹細胞を用いた特発性大腿骨頭壊死症に対する治療法の開発」課題番号20K17992\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-20K17992/20K17992seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00058952","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=60823010"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=60823010","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-20K17992/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-20K17992/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-20K17992/20K17992seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-20K17992/20K17992seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"上岡, 顕"}],"nameIdentifiers":[{"nameIdentifier":"94113","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60823010","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=60823010"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-02-16"}],"displaytype":"detail","filename":"ME-PR-UEOKA-K-kaken 2022-4p.pdf","filesize":[{"value":"226.2 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-UEOKA-K-kaken 2022-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/52658/files/ME-PR-UEOKA-K-kaken 2022-4p.pdf"},"version_id":"83377864-b5eb-4e0b-80c4-f9333a8bda24"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"独自開発したシート状脂肪幹細胞を用いた特発性大腿骨頭壊死症に対する治療法の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"独自開発したシート状脂肪幹細胞を用いた特発性大腿骨頭壊死症に対する治療法の開発"},{"subitem_title":"Development of a treatment for idiopathic osteonecrosis of the femoral head using sheet adipose stem cells","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["4085"],"pubdate":{"attribute_name":"公開日","attribute_value":"2023-02-16"},"publish_date":"2023-02-16","publish_status":"0","recid":"52658","relation_version_is_last":true,"title":["独自開発したシート状脂肪幹細胞を用いた特発性大腿骨頭壊死症に対する治療法の開発"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-07-01T05:18:14.116379+00:00"}