{"created":"2023-07-27T06:56:23.078706+00:00","id":53228,"links":{},"metadata":{"_buckets":{"deposit":"cf127345-d1fa-4560-ac98-658837fc431b"},"_deposit":{"created_by":18,"id":"53228","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"53228"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00053228","sets":["2812:2813:2820"]},"author_link":["45087","94640"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-05-23","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2010-04-01 – 2014-03-31","bibliographic_titles":[{"bibliographic_title":"平成25(2013)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2013 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"WT1の発現は64症例（91％）に確認された。殆どすべての症例で、WT1発現は腫瘍細胞の細胞質に認められた。腫瘍細胞のWT1発現量はFIGO手術進行期分類stageII以上の進行群、子宮筋層浸潤を1/2以上認める群、分化度grade2以上の組織型高分化群で高値であった。MVDはFIGO手術進行期分類stageII以上の進行群、子宮筋層浸潤を1/2以上認める群、分化度grade2以上の組織型高分化群で高値であった。\nWT1とMVDとの間には正の相関関係が認められ、免疫組織化学染色でWT1とVEGFが同一部位に発現していることを確認した。","subitem_description_type":"Abstract"},{"subitem_description":"A strong association was found between WT1 expression score and mean vascular density. Immunohistochemistry of serial sections revealed that WT1 and VEGF were co-expressed in the same area of endometrial cancer tissue.\nTumor-produced WT1, which may regulate the expression of VEGF, is found to be associated with induction of angiogenesis in endometrial cancer.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:22791522, 研究期間(年度):2010-04-01 – 2014-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：「子宮体癌におけるWilms腫瘍遺伝子と細胞増殖及び血管新生での分子生物学的解明」研究成果報告書　課題番号22791522\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所））\n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-22791522/22791522seika/)を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00059512","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/search/?kw=90547184"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/search/?kw=90547184","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-22791522/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-22791522/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-22791522/22791522seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-22791522/22791522seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-05"}],"displaytype":"detail","filename":"HO-PR-DOHI-S-kaken 2014-4p.pdf","filesize":[{"value":"157.6 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-DOHI-S-kaken 2014-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/53228/files/HO-PR-DOHI-S-kaken 2014-4p.pdf"},"version_id":"822f23a4-fa5a-492d-ac13-09fe367151f6"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"子宮体癌におけるWilms腫瘍遺伝子と細胞増殖及び血管新生での分子生物学的解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"子宮体癌におけるWilms腫瘍遺伝子と細胞増殖及び血管新生での分子生物学的解明"},{"subitem_title":"Molecular biological approach to correlation between WT1 gene and cell proliferation, angiogenesis in Endometrial cancer","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2820"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-10-05"},"publish_date":"2020-10-05","publish_status":"0","recid":"53228","relation_version_is_last":true,"title":["子宮体癌におけるWilms腫瘍遺伝子と細胞増殖及び血管新生での分子生物学的解明"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T09:13:17.263171+00:00"}